patients and methods in this cross-sectional study, the hemoglobin levels of 52 patients with end-stage renal disease were measured before and after hemodialysis. the required erythropoietin doses and the differences in cost were calculated based on the hemoglobin levels before and after hemodialysis. a model to predict the adjusted erythropoietin dosages based on post-hemodialysis hemoglobin l...

conclusions this case report supports the beneficial role of erythropoietin in function, maintenance, and recovery of neurons. erythropoietin is a double-edge sword, as long-term erythropoietin therapy has some complications, like thromboembolism and stroke. recent studies suggested that erythropoietin should be given as single high dose to exert a rapid neuro-protective effect with minimal hem...

Purpose: Microgravity causes major changes in various systems of the body in space, such as shift in cerebrospinal fluid, decreased red blood cells count, and electrolyte loss. These complications are very important in space and we should find new approaches to prevent the side effects of microgravity in astronauts. Materials and Methods: This experimental study was conducted on 21 adult ma...

 ABSTRACT Background: Very low birth weight infants ( <1500 g) frequently require blood transfusions because of repeated blood sampling accompanied by anemia of prematurity. Methods: In an attempt to identify the effect of human recombinant erythropoietin to decrease the requirement for blood transfusions, erythropoietin was administered to 24 pre term infants less than 1500 g prospectively fro...

Objective(s): Increasing evidence in both experimental and clinical studies suggests that oxidative stress plays a major role in the pathogenesis of multiple sclerosis. The aim of the present work is to investigate the protective effects of erythropoietin against cuprizone-induced oxidative stress. Materials and Methods: Adult male C57BL/6J mice were fed a chow containing 0.2 % cuprizone for 6 ...

background and purpose: kidney failure reduces the kidney function and in long term it leads to chronic kidney disease. one of the main complications of this disease is irreversible damage to the kidneys (end-stage kidney disease) and hemodialysis is the main method used to treat advanced kidney failure. the main problem associated with hemodialysis is treating anemia caused by lack of erythrop...

Background: The aim of this study was to determine the frequency of resistance to synthetic erythropoietin and factors affecting it among chronic hemodialysis patients in Kerman/ Iran. Methods: This cross- sectional study was performed on chronic hemodialysis patients of three hemodialysis centers in Kerman, Iran during 3 successive months in the summer of 201...