BACKGROUND Chinese menopausal women comprise a large population and the women in it experience menopausal symptoms in many different ways. Their health related quality of life (HRQOL) is not particularly well studied. Our study intends to evaluate the influence of menopause on HRQOL and explore other risk factors for HRQOL in rural China. METHODS An interview study was conducted from June to ...

The Oxford hip score (OHS) is a patient-based instrument for assessment of outcome which is often used after total hip replacement, and the EuroQol 5D (EQ5D) is a patient-based generic questionnaire for health assessment. In an analysis of the outcome at one year of 609 revision hip replacements (RHRs), we compared the OHS and EQ5D scores, postoperative patient satisfaction and change in pain. ...

BACKGROUND The need for cost effectiveness analyses in randomized controlled trials that compare treatment options is increasing. The selection of the optimal utility measure is important, and a central question is whether the two most commonly used indexes - the EuroQuol 5D (EQ5D) and the Short Form 6D (SF6D) - can be used interchangeably. The aim of the present study was to compare change sco...

OBJECTIVE Treatment in general is mostly directly aimed at disease activity, and measures such as the DAS28 might therefore present important additional information. Our aim was to develop and validate a model that uses a combination of disease activity (DAS28) and HAQs to estimate EuroQoL 5-dimension scale (EQ5D) utilities. METHODS Longitudinal data from a cohort study in RA patients from th...

Results: Patient demographics40 patients (35Female/5Male) (19Left +21Right). Average age60.7 years (Range 29-88). No bilateral procedures. 32/40 (80%) patients showed improvement in all three MOxFQ domains. MOXFQ scores showed significant improvement post-operatively. Pain-51.6 (5-100) to 24.4 (0-100), walking-51.4 (0-96) to 22.9 (0-86). Social interaction48.8 (0-100) to 23.1 (range 0-88). p< 0...

Background Estimating cost-effectiveness in the treatment of rheumatoid arthritis (RA) has received increasing attention recent years as a large number new drugs have been developed and generated through huge development costs soaring drug costs. Objectives EuroQol-5th dimension score (EQ5D) is most popular index for measuring quality life patients with (RA). In this study, an association betwe...

BACKGROUND Our purpose is to examine the relationship of Health related quality of life measured by EORTC QLQc30, QLQ-LC13; FACT-L, LCSS, Eq5D) with survival in advanced lung cancer patients. A total of 299 Lung Cancer (LC) patients were, included in this national multicenter Project entitled of "the LC Quality of Life Project (AKAYAK). Baseline scores were analyzed by using Cox's proportional ...

BACKGROUND Economic costs related to treatment of multiple sclerosis (MS) must be justified by health state, quality of life (QOL) and social participation improvement. This study aims to describe correlations between social participation, economic costs, utility and MS-specific QOL in a sample of patients with MS (pwMS). METHODS We interviewed 42 pwMS receiving natalizumab and collected clin...

Evaluation of interventions to enhance recruitment or reduce attrition within randomised controlled trials is uncommon. A number of initiatives have tried to increase this evidence base by encouraging the embedding of such trials within trials evaluating healthcare interventions. The NIHR-funded REFORM study recruited and followed up participants by mailing out invitation packs and questionnair...