نتایج جستجو برای: epitope prediction

تعداد نتایج: 271735  

Journal: :iranian journal of applied animal science 2015
s. yousefi m. tahmoorespur m.h. sekhavati

brucellosis, produced by brucella species, is a disease that causes severe economic losses for livestock farms worldwide due to serious economic and medical consequences of this disease, many efforts have been made to prevent the infection through the use of recombinant vaccines based on brucella outer membrane protein (omp) antigens. in the present study, a wide range of on-line prediction sof...

M. Tahmoorespur, M.H. Sekhavati S. Yousefi,

Brucellosis, produced by Brucella species, is a disease that causes severe economic losses for livestock farms worldwide Due to serious economic and medical consequences of this disease, many efforts have been made to prevent the infection through the use of recombinant vaccines based on Brucella outer membrane protein (OMP) antigens. In the present study, a wide range of on-line prediction sof...

Journal: :novelty in biomedicine 0
mohammad mehdi ranjbar razi vaccine and sera institute, karaj, iran sedigheh nabian department of parasitology, tick and tick-borne diseases center, faculty of veterinary medicine, university of tehran, tehran, iran nayeb ali ahmadi proteomics research center, faculty of paramedical sciences, shahid beheshti university of medical sciences, tehran, iran khodayar ghorban department of immunology, aja university of medical sciences, tehran, iran alireza sazmand department of agriculture, payame noor university-yazd brancesh, yazad, iran maryam dadmanesh department of infectious diseases, aja university of medical sciences, tehran, iran

background: dermatophagoides farinae and dermatophagoides pteronyssinus are house dust mites (hdm) that they cause severe asthma and allergic symptoms. tropomyosin protein plays an important role in mentioned immune and allergic reactions to hdms. here, tropomyosin protein from dermatophagoides spp. was comprehensively screened in silico for its allergenicity, antigenicity and similarity/conser...

Journal: :vaccine research 0
f badmasti department of bactriology, pasteur institute of iran, tehran, iran sd siadat department of bactriology, pasteur institute of iran, tehran, iran s bouzari department of molecular biology, pasteur institute of iran, tehran, iran o nasiri department of bactriology, pasteur institute of iran, tehran, iran h nemati department of bactriology, pasteur institute of iran, tehran, iran f shahcheraghi department of bactriology, pasteur institute of iran, tehran, iran

introduction: acinetobacter baumannii is associated with hospital-acquired infections. outer membrane protein a of a.baumannii (abompa) is a well-characterized virulence factor which has important roles in pathogenesis of this bacterium. methods: based on our pcr-sequencing of ompa gene in the clinical isolates, abompa protein can be categorized into two types, named here type-1 and type-2. we ...

Background: Multiple sclerosis (MS) is the most common autoimmune disease of the central nervous system (CNS). The main cause of the MS is yet to be revealed, but the most probable theory is based on the molecular mimicry that concludes some infections in the activation of T cells against brain auto-antigens that initiate the disease cascade.Objectives: The Purpose of this research is the...

Journal: :Genome informatics. International Conference on Genome Informatics 2007
Jian Huang Wataru Honda Minoru Kanehisa

We evaluate the performance of six amino acid indices in B cell epitope residue prediction using the classical sliding window method on five data sets. Four of the indices: i.e. relative connectivity, clustering coefficient, closeness and betweenness are newly derived from the topological parameters of residue networks. The other two are Parker's hydrophilicity and Levitt's index, known as the ...

Journal: :applied biotechnology reports 0
elaheh sabbaghian fatemeh roodbari alireza rafiei jafar amani

human cytomegalovirus is one of the most common pathogenic viruses all over the world. in congenital infection leads to neurologic severe disorders and even death of fetus and in individuals with immunosuppression may also cause severe clinical symptoms. multiple evidence indicate that among several strategies, epitope-based vaccine (evs) that can induce both humoral and cellular immunity respo...

2016
Chunhua Zhang Yunyun Li Weina Tang Zhiguo Zhou Pingping Sun Zhiqiang Ma

B-cell epitope is a group of residues which is on the surface of an antigen. It invokes humoral responses. Locating B-cell epitope is important for effective vaccine design, and the development of diagnostic reagents. Mimotope-based B-cell epitope prediction method is a kind of conformational B-cell epitope prediction, and the core idea of the method is mapping the mimotope sequences which are ...

2008
Qing Zhang Peng Wang Yohan Kim Pernille Haste-Andersen John E. Beaver Philip E. Bourne Huynh-Hoa Bui Søren Buus Sune Pletscher-Frankild Jason Greenbaum Ole Lund Claus Lundegaard Morten Nielsen Julia V. Ponomarenko Alessandro Sette Zhanyang Zhu Björn Peters

We present a new release of the immune epitope database analysis resource (IEDB-AR, http://tools.immuneepitope.org), a repository of web-based tools for the prediction and analysis of immune epitopes. New functionalities have been added to most of the previously implemented tools, and a total of eight new tools were added, including two B-cell epitope prediction tools, four T-cell epitope predi...

2013
Bo Yao Dandan Zheng Shide Liang Chi Zhang

Accurate prediction of B-cell antigenic epitopes is important for immunologic research and medical applications, but compared with other bioinformatic problems, antigenic epitope prediction is more challenging because of the extreme variability of antigenic epitopes, where the paratope on the antibody binds specifically to a given epitope with high precision. In spite of the continuing efforts ...

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