perivascular epithelioid cell tumor (pecoma) is a rare mesenchymal tumor composed of immunohistochemically and histologically distinctive perivascular epithelioid cells. here, we report on the computed tomography (ct) and magnetic resonance imaging (mri) findings of ovarian pecoma with pulmonary metastasis. the tumor was visible as a multilocular hemorrhagic mass that encased the ovarian vessel...

Epithelioid hemangioendothelioma is a vascular tumor with an intermediate malignant potential. This tumor is very rare in the lung parenchyma, and most of the previously reported cases have been asymptomatic. There is no standard therapy for this tumor and prognosis in the previous reports has been variable.Herein we report our experience with a 60-year-old woman presenting with hemoptysis and ...

perivascular epithelioid cell tumor (pecoma) is composed of hmb45+ epithelioid cells with clear to granular cytoplasm and perivascular distribution. we describe a uterine pecoma in a 33 years old woman where tumor cells were positive for hmb45 but negative for epithelial markers and negative or positive for smooth muscles markers.

epithelioid hemangioendothelioma is a vascular tumor with an intermediate malignant potential. this tumor is very rare in the lung parenchyma, and most of the previously reported cases have been asymptomatic. there is no standard therapy for this tumor and prognosis in the previous reports has been variable. herein we report our experience with a 60-year-old woman presenting with hemoptysis and...

Background and aims: Epithelioid granulomas is one of the best histological criterion for distinguishing Crohn’s disease (CD) from other inflammatory bowel diseases. Few data are available on the time of occurrence of epithelioid granulomas, and the value of epithelioid granulomas in predicting outcome has been determined only in cohorts of prevalent CD cases. Our objective was to evaluate epit...

Background To develop cancer antigen-targeted immunotherapeutic strategies for malignant pleural mesothelioma (MPM), we investigated the individual and coexpressions of the cancer-associated antigens mesothelin (MSLN), cancer antigen 125 (CA125), and Wilms tumor 1 (WT1) in both epithelioid and non-epithelioid MPM. Methods All available hematoxylin and eosin-stained slides from patients who we...

Endothelial cells distinguished by their epithelioid morphology have been recognized for many years. Rosai first characterized them as “histiocytoid” in appearance in 1979 and soon thereafter they became known by the more popularized term "epithelioid". By the early and mid 1980's this nomenclature was incorporated into classification schemes of epithelioid vascular tumors that included reactiv...

Epithelioid sarcoma is a rare soft tissue neoplasm that usually arises in the distal extremities of young adults. Epithelioid sarcoma presents a high rate of recurrences and metastases and frequently poses diagnostic dilemmas. We previously reported loss of tumor suppressor SMARCB1 protein expression and SMARCB1 gene deletion in themajority of epithelioid sarcoma cases. Unfortunately, no approp...

Epithelioid sarcoma is a rare soft tissue neoplasm that usually arises in the distal extremities of young adults. Epithelioid sarcoma presents a high rate of recurrences and metastases and frequently poses diagnostic dilemmas. We previously reported loss of tumor suppressor SMARCB1 protein expression and SMARCB1 gene deletion in the majority of epithelioid sarcoma cases. Unfortunately, no appro...