objective in this study, we investigated the changes of the serum levels of thyroidhormones including thyroxine (t4), triiodothyronine (t3), t3 resin uptake andthyroid stimulating hormone (tsh) in epileptic children during treatment withanti-epileptic drugs (aeds) including carbamazepine (cbz), primidone (prm),phenobarbital and valproic acid (vpa). materials and methods this study consisted of ...

the occurrence of neonatal seizures may be the first and perhaps, the only clinical sign of a central nervous system (cns) disorder in the newborn infant. identifying the etiology for the neonatal seizures is/critical to prognosis and treatment. the most common etiology for neonatal seizures is hypoxic-ischemic encephalopathy. seizures may indicate the presence of a potentially treatable etiolo...

how to cite this article: ghofrani m. approach to the first unprovoked seizure- part ii. iran j child neurol. 2013 autumn; 7(4):1-5. abstract the approach to a child who has experienced a first unprovoked generalized tonic-clonic seizure is challenging and at the same time controversial. how to establish the diagnosis, ways and means of investigation and whether treatment is appropriate, are di...

how to cite this article: ghofrani m. approach to the first unprovoked seizure- part i. iran j child neurol. 2013 summer; 7(3): 1- 5.   the approach to a child who has experienced a first unprovoked generalized tonic-clonic seizure is challenging and at the same time controversial. how to establish the diagnosis, ways and means of investigation and whether treatment is appropriate, are differen...

background: the physiologic function of carnitine, oxidation of fatty acid and lipid  metabolism, is severely affected in carnitine deficiency, secondary forms of which lead to renal tubular disorders and chronic renal failure. reduction in serum carnitine has been frequently reported in patients and experimental animals treated with antiepileptic drugs, one of which, valproic acid has consiste...

Epilepsy is one of the most important diseases of nervous system that involves 0.5-1% of the population. In spite of new developments in antiepileptic drugs, between 20-30% of epileptic patients can not be controlled and even those who are controlled with antiepileptic drugs suffer from their adverse events. Epileptic patients have different challenges in relation to the disease and its medicat...

Although treated properly for epilepsy, a number of epileptic children have intractable seizures and about 5-10 per cent of them do not respond to anti -epileptic drugs. In the years 1986-1996 about 10,000 epileptic patients were treated in the Children's Medical Center in Tehran. A retrospective study of their medical records revealed that 41 of them had intractable seizures. I Of these 4...

although treated properly for epilepsy, a number of epileptic children have intractable seizures and about 5-10 per cent of them do not respond to anti -epileptic drugs. in the years 1986-1996 about 10,000 epileptic patients were treated in the children's medical center in tehran. a retrospective study of their medical records revealed that 41 of them had intractable seizures. i of these 4...