Background and Objectives: Apoptosis of eosinophils is of significant value in assessing the airway inflammation in patients with asthma. Our purpose was to investigate the degree of expression of the Bcl-2 protein in sputum eosinophils during acute asthma exacerbation and its relationship with exacerbation severity.    Materials and Methods: The study was carried out in Mostafa Khomeini Ho...

background and objectives: apoptosis of eosinophils is of significant value in assessing the airway inflammation in patients with asthma. our purpose was to investigate the degree of expression of the bcl-2 protein in sputum eosinophils during acute asthma exacerbation and its relationship with exacerbation severity.    materials and methods: the study was carried out in mostafa khomeini hospit...

Introduction: Although recent studies show the association of eosinophils with different tumors including oral malignancies, the role of eosinophils in premalignant conditions of the oral cavity is not known precisely. Therefore, this study aimed to determine the number of eosinophils in premalignant and malignant conditions of the oral cavity and its role in progression to malignancy. Materia...

Abstract Background Numerous disorders can cause recurrent abdominal pain. Many of these cases underwent endoscopy and clinician encounters patients with history of recurrent abdominal pain and normal endoscopy. We evaluated these biopsies with regard to their eosinophils and mast cell densities to find out a potential relationship between recurrent abdominal pain with eosinophils and mast ce...

abstract background numerous disorders can cause recurrent abdominal pain. many of these cases underwent endoscopy and clinician encounters patients with history of recurrent abdominal pain and normal endoscopy. we evaluated these biopsies with regard to their eosinophils and mast cell densities to find out a potential relationship between recurrent abdominal pain with eosinophils and mast cell...

Eosinophils differentiate and mature in the thymus, outside of bone marrow, healthy individuals. Locally developed thymic eosinophils may contribute to maturation selection human thymocytes.

allergic airway inflammation is characterized by elaboration of cytokines and chemokines leading to recruitment of inflammatory leukocytes, predominantly eosinophils, to the airways. granulocyte macrophage colony stimulating factor (gm-csf) is generated in the lungs of human subjects with asthma in response to allergen challenge and is necessary for the development of allergen-induced bronchial...

â  â  background eosinophilic gastroenteritis (eg) is a rare inflammatory disorder of the gastrointestinal (gi) tract. there have been several case series of patients with eg from the western world and east asia. however, there has not been a report of patients with eg from the middle east region. the aim of this study is to describe clinical characteristics and treatment response in a series o...