angiotensin i-converting enzyme (ace) gene polymorphism; genotype dd or d allele may be involved with an increased susceptibility to type 2 diabetes and diabetic nephropathy (dn). we examined the frequency of ace gene polymorphism in 170 patients (85 type 2 diabetes with nephropathy and 85 without it) in tehran, iran. dna was extracted from the white blood cells and the i/d polymorphism of the ...

background: sarcoidosis is a multisystem inflammatory disease of unknown origin with characterization of small granulomas. angiotensin-converting enzyme (ace) is a pathophysiologic marker of sarcoidosis. we present the ace insertion/deletion (i/d) polymorphism in correlation with serum ace level in iranian patients with sarcoidosis. methods: from jan 2014 to jan 2015, 102 iranian patients who h...

The CYP2A6 gene, which codes the enzyme, has known to have ahigh polymorphism. This polymorphism could decrease, increase, or eliminate enzyme activity. CYP2A6*4 , an inactive allele, decreased One of enzyme-specific substrates is nicotine. allele decrease nicotine metabolism that causes high levels in blood. In addition, it caused increasing Low-Density Lipoprotein Cholesterol (LDL-C) by expan...

the activity of angiotension converting enzyme (ace; omim: 106180) in different brain regions of patients with schizophrenia changed, suggesting a possible involvement of ace in psychiatric disorders. genetic polymorphism of insertion/deletion (i/d; dbsnp rs4646994) in the gene encoding ace has been well defined.the present case-control study was performed on 363 (268 males, 95 females) in-pati...

Background: Angiotensin converting enzyme (ACE) is the key enzyme, regulates blood pressure which encoded by 21kb gene that consists of 26 exons and located on chromosome 17, contains a polymorphism in form either Insertion (I) or Deletion (D). The aim was to study effect antihypertensive drugs patients essential hypertension associated with ACE polymorphism. Methods: Hypertensive were recruite...

purpose it is well known that the effects of exercise training gives inter individual differences which might be due to genetic diversity. this study aims to explore the probable relation between angiotensin converting enzyme (ace) alleles and physical fitness parameters in elite athletes. methods twenty-nine national level indian army triathletes who volunteered for the study were taken as sub...

Objective: The paraoxonase 1 (PON-1) enzyme is an important antioxidant. balance between oxidative stress and antioxidant defense mechanisms disturbed during asthma attacks. activity of the PON-1 related to gene polymorphism. This study aimed evaluate Q192R polymorphism in asthmatic children. Material methods: During 2013-2014 period, we performed a prospective with 34 (study group) healthy (co...