The exposome concept was defined in 2005 as encompassing all environmental exposures from conception onwards, as a new strategy to evidence environmental disease risk factors. Although very appealing, the exposome concept is challenging in many respects. In terms of assessment, several hundreds of time-varying exposures need to be considered, but increasing the number of exposures assessed shou...

Edi tor 's Note : NEHA strives to provide up-to-date and relevant in­ formation on environmental health and to build partnerships in the profes­ sion. In pursuit of these goals, we feature a column from the Environmental Health Services Branch (EHSB) of the Centers for Disease Control and Pre­ vention (CDC) in every issue of the Journal. In this column, EHSB and guest authors from across CDC wi...

background: hairdressers are occupationally exposed to a number of agents in their workplace that result in respiratory symptoms and changes in pulmonary function. objective: to evaluate associations between occupational exposure and respiratory function and reported symptoms in a group of hairdressers compared to a control group. methods: a questionnaire on respiratory symptoms and workplace c...

introduction: nickel (ni) is one of the toxic heavy metals that exposure to it has been connected with chronic respiratory complications such as asthma, chronic bronchitis, lung cancer and heart disease. in this research, original studies that investigated occupational or environmental exposure to nickel and  measured nickel levels in human tissues were reviewed. materials and methods: in this ...

A brief review is given of data analysis methods for the identification and quantification of associations between environmental exposures and health events of interest. Data analysis methods are outlined for each of the study designs mentioned, with an emphasis on topics in need of further research. Particularly noted are the need for improved methods for accommodating exposure assessment meas...

This paper discusses the principles of study design and related methodologic issues in environmental epidemiology. Emphasis is given to studies aimed at evaluating causal hypotheses regarding exposures to suspected health hazards. Following background sections on the quantitative objectives and methods of population-based research, we present the major types of observational designs used in env...

this study investigates the effectiveness of the kriging interpolation model and the emission weighted proximity model (ewpm) in assessing relative exposure risk of air pollution using results from the american meteorological society/epa regulatory model (aermod) as benchmarks. we used simulated exposure risk to so2 in the dallas area in texas in this evaluation. results suggest that the relati...

introduction:. nickel (ni) is one of the toxic heavy metals that exposure to it has been connected with chronic respiratory complications such as asthma, chronic bronchitis, lung cancer and heart diseases .. in this research,  original studies that investigated occupational or environmental exposures to nickel and  measured nickel levels in human tissues was reviewed. materials and methods: in ...

testicular cancer is one of the commonest cancers in men of working age, and is increasing in incidence in europe and north america. one suggested mechanism of causation is that there is impaired differentiation of germ cells in the pre- or perinatal period, followed by malignant transformation in later life, possibly by a hormonal mechanism. endocrine disrupting chemicals (edcs) have been a ma...