suicide is a major public health concern, with approximately one million people committing suicide world-wide each year .risk factors for suicidal behavior include, psychiatric and medical illness, impulsivity, aggression, alcohol and drug abuse specially stimulants, and  stress. neurobiological, brain mappings and biochemical studies have revealed that suicide victims experiencing a large numb...

conclusions some results of the correlation coefficients are not the same with visualization. the reason may be due to the small number of data. materials and methods in the foundation-application study, we constructed two-way gene networks using nonparametric methods, such as spearman’s rank correlation coefficient and blomqvist’s measure, and compared them with pearson’s correlation coefficie...

Gene Ontology (GO)-based statistical enrichment analysis is a popular approach to identify statistically enriched biological processes, molecular functions, and cellular components that are associated with a list of genes. However, such GO enrichment analysis often generates a large number of enriched GO terms that are difficult to interpret and analyze. To address this issue, we developed GOfo...

Light quality is a key environmental factor affecting plant growth and development. In this study, RNA-seq technology was used to explore the molecular mechanisms of ginkgo metabolism under different monochromatic lights. Leaves were for transcriptome sequencing analysis after being irradiated by red, blue, white LED After treatment, 2040 differentially expressed genes (DEGs) identified. Gene O...

background alcoholic hepatitis (ah) is an acute manifestation of alcoholic liver disease with high mortality rates. objectives our aim was to study the molecular mechanisms of ah. materials and methods the differentially expressed genes (degs) in liver between ah and control cases were identified by analyzing the gse28619 microarray data using t-test. the kyoto encyclopedia of genes and genomes...

Objective(s): The purpose of this study was to conduct a meta-analysis on human microRNAs (miRNAs) expression data of endometriosis tissue profiles versus those of normal controls and to identify novel putative diagnostic markers. Materials andMethods: PubMed, Embase, Web of Science, Ovid Medline were used to search for endometriosis miRNA expression profiling studies of endometriosis. The miRN...

objective(s): the purpose of this study was to conduct a meta-analysis on human micrornas (mirnas) expression data of endometriosis tissue profiles versus those of normal controls and to identify novel putative diagnostic markers. materials andmethods: pubmed, embase, web of science, ovid medline were used to search for endometriosis mirna expression profiling studies of endometriosis. the mirn...

We develop a flexible, open-source framework for query answering on relational databases by adopting methods and techniques from the Semantic Web community data exchange community, we apply this to medical use case. first deploy module-extraction derive concise relevant sub-ontology an external reference ontology. then chase procedure materialize universal solution that can be subsequently used...