The interaction between engineered nanoparticles and the bacterial lipopolysaccharide, or endotoxin, is an event that warrants attention. Endotoxin one of most potent stimulators inflammation immune reactions in human beings, a very common contaminant research labs. In nanotoxicology nanomedicine, presence endotoxin on nanoparticle surface affects their biological properties leading to misinter...

The significance of endotoxin-free, sterile dialysis fluid for long-term, high-quality hemodialysis treatment is obvious and highly desired[MF1] . current study aimed to determine endotoxin the water quality used in twenty centers. Eighty samples (40 x dialysates 40 water) were tested using LAL gel clot method. results revealed a variation produced that makes it unaccepted compared internationa...

The aim of the present study was to compare the ability of the commercially available portable test system (PTS(TM)) to detect endotoxin activity in bovine serum, with that of the traditional LAL-kinetic turbidimetric (KT) and chromogenic (KC) assays. Prior to testing, serum samples, which were obtained from endotoxin-challenged cattle, were diluted 1:20 in endotoxin-free water and heated to 80...

the endotoxin dose response of recruited and activated tissue macrophages isolated from a rat model of liver injury has been measured after 24 hours in in vitro culture, with respect to their production of a lysosomal enzyme, n-acetyl-glucosaminidase (tlag). there were no significant differences in the nag activity in cell lysates or supernatants following a two-hour exposure of the macrophages...

Agricultural operations and the processing sector generate dust laden with endotoxin in workplace. Endotoxin, a pro-inflammatory agent, has adverse effects on health, especially lungs, as exposure to reduces lung function capacity. Endotoxin workers its harmful impact health of agricultural needs be studied detail for future interventions reduce endotoxin. The review can help identify analytica...

our prior study found  that transforming growth factor  beta-induced (tgfbi) is  an important negative regulator in tlr-induced inflammation. however, whether tgfbi may affect inflammation during lipopolysaccharide (lps)-induced endotoxin tolerance (et) is still unclear.this study aimed to investigate whether tgfbi was involved in the mechanisms of et in human through dampening nuclear factor-k...

Background: Hepatic encephalopathy is defined as a neuropsychiatric brain dysfunction in acute or chronic liver failure. Infection and inflammation have crucial role in its pathophysiology. The purpose of our study was to demonstrate the relationship between toll-like receptor 4 (TLR4) expression and the encephalopathy induced with endotoxin in biliary cirrhotic rats. Methods: The present stud...

introduction: presently, bacteremia is the principal cause of morbidity in patients undergoing hemodialysis. gram-negative bacteria account for approximately 50 percent of documented infections. endotoxins released during lysis of gram negative bacteremia result in inflammatory and defense response by the body and if not treated promptly result in septic shock and ultimately death of the patien...

conclusions in this study, the l-lps immune response of bovine cells was significant, indicating that tlr2 is the predominant receptor for l-lps. due to l-lps endotoxin-like activity, we found a strategy through using bmap-28 to prevent l-lps-induced tlr2-dependent immune activation in bovine cells. materials and methods in this study, l-lps-induced proinflammatory cytokine production in bovine...