BACKGROUND To study the incidence of non-endometrioid carcinoma of endometrium and compare the clinical characteristics and treatment outcomes with endometrioid carcinoma patients. MATERIALS AND METHODS This study included 236 patients with endometrial carcinoma at Siriraj Hospital whom were diagnosed and treated from 2003 through 2006. The clinical characteristics, pathological features, tre...

In 2006, dedifferentiated endometrioid adenocarcinoma (undifferentiated carcinoma associated with low-grade endometrioid carcinoma) of the uterus was first proposed. Dedifferentiated endometrioid carcinoma is part of the spectrum of undifferentiated carcinoma of the endometrium which is a highly aggressive tumor even when the undifferentiated component represents only 20% of the entire neoplasm...

Objective: The aim was to detect the expression of PR and CD146 in paraffin-embedded tissue sections of endometrioid adenocarcinoma by using QDs double-labeling immunofluorescence, and evaluate the applied value of QDs double-labeling immunofluorescence in endometrioid adenocarcinoma. Methods: To detect the expression of PR and CD146 on 140 cases of paraffin-embedded tissue sections of endometr...

Background: Endometrial carcinoma is the most common malignancy in the female genital tract and associated with considerable degree of morbidity. Endometrial carcinoma has traditionally been divided into type I and type II cancers. Type I tumors are low grade endometrioid carcinoma that frequently arise in a setting of excess estrogen and associated with good clinical outcome while type II are ...

OBJECTIVE This study aims to investigate the expression of γ-synuclein in endometrioid endometrial carcinoma and assess if the γ-synuclein expression correlates with the aggression of the tumour and its prognostic value in endometrioid endometrial carcinoma. DESIGN This retrospective study evaluated (60) specimens of the primary untreated endometrioid endometrial carcinoma and (12) normal end...

CONTEXT Diagnostic staging is an important prognostic factor for endometrial adenocarcinoma. Apart from the histological type and histological grade, some markers seem to be associated with the stage and biological behavior of the disease. Among these are p53, estrogen and progesterone receptors. OBJECTIVE The objectives of the present study were: to compare histological type and grading of e...

Background: A 54 year female presented with distension of abdomen, and weight loss. Abdominal ultrasonography revealed Bilateral Ovarian carcinoma. Patient was operated and specimen received to the department of Pathology. The resected specimen showed two large ovarian masses, on cut open solid and cystic areas seen. Histologically tubular pattern of tumor tissue seen with no endometriotic (end...

•Dedifferentiated endometrioid adenocarcinoma is characterized by the coexistence of an undifferentiated carcinoma and a low-grade endometrioid adenocarcinoma.•Given its histological appearance, this tumor can be mistaken for other less aggressive tumors.•The possibility of undifferentiated carcinoma should be considered in endometrioid carcinoma with patterns of solid growth without appreciabl...

Loss of heterozygosity (LOH) at locus 10q23.3 and mutation of the PTEN tumor suppressor gene occur frequently in both endometrial carcinoma and ovarian endometrioid carcinoma. To investigate the potential role of the PTEN gene in the carcinogenesis of ovarian endometrioid carcinoma and its related subtype, clear cell carcinoma, we examined 20 ovarian endometrioid carcinomas, 24 clear cell carci...