The armadillo could be considered as an experimental model for leprosy studies. Mycobacterium leprae main host cells are macrophages and Schwann cells. However, endocytosis and germicidal activities of armadillo macrophages and monocytes have not yet been evaluated. The aim of this research was to evaluate endocytosis and NBT-reduction activities of monocyte-derived macrophages (MDM) and monocy...

the armadillo could be considered as an experimental model for leprosy studies. mycobacterium leprae main host cells are macrophages and schwann cells. however, endocytosis and germicidal activities of armadillo macrophages and monocytes have not yet been evaluated. the aim of this research was to evaluate endocytosis and nbt-reduction activities of monocyte-derived macrophages (mdm) and monocy...

Endocytosis is a crucial component of many pathological conditions. The proximal tubules are responsible for reabsorbing the majority filtered water and glucose, as well all proteins through glomerular barrier via endocytosis, indicating an essential role in kidney diseases. Genetic mutations or acquired insults could affect tubule endocytosis processes, by disturbing overstressing endolysosoma...

Background and Purpose The ?4?2 nicotinic ACh receptor (nAChR), a subtype of the ligand-gated ion channel, is abundantly expressed in brain implicated several neurological disorders. endocytosis nAChRs plays important roles pathogenesis diseases, but underlying molecular mechanisms remain poorly understood. Experimental Approach Loss-of-function approaches mutants that display different endocyt...

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of COVID-19, so understanding its biology and infection mechanisms critical to facing this major medical challenge. SARS-CoV-2 known use spike glycoprotein interact with cell surface as a first step in process. As for other coronaviruses, it likely that next undergoes endocytosis, but whether or not required inf...

the wharton’s jelly of the umbilical cord is believed to be a source of mesenchymal stem cells (mscs) which can be therapeutically applied in degenerative diseases. in this study, we investigated the immunomodulatory effect of umbilical cord derived- mesenchymal stem  cells (uc-mscs) and  bone  marrow-derived-mesenchymal stem  cells (bm-mscs) on differentiation, maturation, and endocytosis of m...

Peptide-binding assays suggest that SARS-CoV-2 receptors engage the endocytosis and autophagy machinery.

Zwitterion Materials In article number 2101407 by Zhonggui He, Jin Sun, and co-workers, prodrug nanoassemblies modified PEG or zwitterion materials are presented as spherical soldiers rod-shaped soldiers. Through the voyage in ocean, which indicates blood circulation, they reach castle, tumors, different ships. Soldiers ashore enter castle through gates, indicate endocytosis mechanisms, to play...

Chemical neurotransmission is the major mechanism of neuronal communication. Neurotransmitters are released from secretory organelles, synaptic vesicles (SVs) via exocytosis into cleft. Fusion SVs with presynaptic plasma membrane balanced by endocytosis, thus maintaining at steady-state levels. The protein machineries responsible for exo- and endocytosis have been extensively investigated. In c...