cycloguanil pamoate was intramuscularly injected into semi-immune people living in the hyper-endemic malarias area. the results showed that a single dose of cycloguanil pamoate by intramuscular injection together with an oral dose of chloroquine, 10 mg/kg body weight, suppressed p. falciparum for at least 3 months and p. vivax for 5 months in bandar abbas, southern iran.

The endemic malarias threaten the several billion people residing where transmission occurs. Chemotherapeutic strategy pitted against these threats hinges upon species- and stage-specific treatments guided by diagnosis and screening against sometime dangerous contraindications. This approach suits malaria as it occurs among travelers in the developed, non-endemic world. However, limiting treatm...

Most malaria diagnosed outside endemic zones occurs in patients experiencing the consequences of what was likely a single infectious bite by an anopheline mosquito. A single species of parasite is nearly always involved and expert opinion on malaria chemotherapy uniformly prescribes species- and stage-specific treatments. However the vast majority of people experiencing malaria, those resident ...

We compare and contrast the results of immunizing mice with irradiated sporozoites of Plasmodium berghei and Plasmodium yoelii. Host genetic control of protective immunity is different in the two rodent malarias. Few mouse strains are strongly protected by P. yoelii sporozoites, while all are protected by P. berghei sporozoite immunization. The role of CD8+ T cells in the protective immune resp...

Fluorochrome staining to detect malaria parasites in bloodfilms is more sensitive, is easier to do, and is less time-consuming than Giemsa staining. However, standard epi-illuminated, mercury vapour, fluorescence microscopes are expensive, especially for tropical countries where malaria is endemic. Fluorescence microscopy with a standard light microscope and a new interference filter specially ...

SUMMARY Different degrees of neurological and psychological problems are observed in endemic goiter inhabitants. To determine the effect of iodine deficiency on IQ, we checked the IQ and size of the thyroid of 194 students of an endemic goiter area and compared with that of 224 students of a non-endemic goiter area in Kohkiloyeh & Boyer Ahmad province. The average IQ of students in endemic goi...