Study Selection Studies were selected if they were randomised controlled trials (RCTs) that compared the outcome when analgesics were given before surgical incision with the outcome when the same medication was given after surgical incision. Studies that compared pre-emptive analgesia with no analgesia or that compared pre-emptive analgesia with pre-emptive analgesia plus analgesia given after ...

Study Selection Studies were selected if they were randomised controlled trials (RCTs) that compared the outcome when analgesics were given before surgical incision with the outcome when the same medication was given after surgical incision. Studies that compared pre-emptive analgesia with no analgesia or that compared pre-emptive analgesia with pre-emptive analgesia plus analgesia given after ...

Introduzione: La chirurgia dentoalveolare, in particolare l’estrazione dei terzi molari mandibolari inclusi, è l’intervento più comunemente eseguito nel campo della Chirurgia Oro-Maxillo-Facciale. Come dimostrato dall’esperienza clinica, questo tipo di intervento può essere gravato da una serie di sequele post-operatorie, di cui la meno tollerata dal paziente è il Dolore Acuto Post-Operatorio (...

To the best of our knowledge, the effect of pre-emptively blocking pain transmission on acute postoperative cognitive dysfunction (POCD) has not yet been assessed. Therefore, the present study aimed to investigate the effect of pre-emptive analgesia via a continuous femoral nerve block (CFNB) on postoperative pain and early cognitive function following total knee arthroplasty (TKA) surgery in e...

BACKGROUND Efficacy of pre-emptive analgesia compared to preventive regimen, managing postoperative pain is still controversial. AIM Evaluating the efficacy of intravenous (IV) paracetamol as pre-emptive analgesia compared to preventive post-treatment administration in pediatric dental setting. DESIGN In a prospective trial, 60 noncooperative children of ASA I, II aged 3-10 years who underw...

background: according to previous studies there are some different opinions on the pre-emptive effects of paracetamol in controlling post-operative pain, we aimed to compare the analgesic effects of pre-emptive paracetamol with post-operative paracetamol and morphine in patients undergoing septorhinoplasty. materials and methods: a hundred and six patients aged 15 to 50 were divided into 3 grou...

Transmission of pain signals evoked by tissue damage leads to sensitization of the peripheral and central pain pathways. Pre-emptive analgesia is a treatment that is initiated before the surgical procedure in order to reduce this sensitization. Owing to this 'protective' effect on the nociceptive system, pre-emptive analgesia has the potential to be more effective than a similar analgesic treat...

Pain from surgical procedures occurs as a consequence of tissue trauma and may result in physical, cognitive, and emotional discomfort. Almost a century ago, researchers first described a possible relationship between intraoperative tissue damage and an intensification of acute pain and long-term postoperative pain, now referred to as central sensitization. Nociceptor activation is mediated by ...