we have now at hand two editions of onsori’s divan , none of them is ideal. this is clauesd, first of all by the corruption of the manuscripts. this article attempts to examine and rectify a number of verses of onsori’s divan which have not been correctly recorded by the editors of the divan in any of its two main editions; the 1st by yahya gharib, edited in 1341 s.h., and the 2nd by mohammad d...

IWATSUKI, N. The Effect of Thiamylal and Propanidid on the Isolated Heart Muscle in Comparison with CT 1341. Tohoku J. exp. Med ., 1973, 110 (1), 3340 Inotropic effects of thiamylal and propanidid on the contractile state of the isolated dog heart muscle were determined by means of force-velocity relations and compared with those of CT 1341, a new steroid anesthetic. All anesthetics studied pro...

IWATSUKI, N. The Effect of CT 1341, a New Steroid Anesthetic, on the Isolated Heart Muscle. Tohoku J. exp. Med., 1973, 109 (1), 69-75 A direct inotropic effect of CT 1341, a new steroid intravenous anesthetic, upon the myocardium was studied in isolated heart muscles of dogs by measurements of force-velocity relation. CT 1341 at the concentrations over 0.139 ml/100 ml caused a dose-dependent le...

Granulomatosis with polyangiitis (GPA) is a potentially lifethreatening ANCA-associated vasculitis (AAV) that typically involves the respiratory tract and the kidney. The introduction of glucocorticoid and CYC therapy in the 1960s dramatically improved the prognosis of affected patients, with 78% surviving at 5 years compared with a 1-year mortality in 80% of untreated patients [1]. No conventi...

Antibody drug conjugates are emerging as a powerful class of antitumor agents with efficacy across a range of cancers; therefore, understanding the disposition of this class of therapeutic is crucial. Reported here is a method of enriching a specific organelle (lysosome) to understand the catabolism of an anti-CD70 Ab-MCC-DM1, an antibody drug conjugate with a noncleavable linker. With such tec...

Citation: Mellor KC, Meyer A, Elkholly DA, Fournié G, Long PT, Inui K, Padungtod P, Gilbert M, Newman SH, Vergne T, Pfeiffer DU and Stevens KB (2018) Comparative Epidemiology of Highly Pathogenic Avian Influenza Virus H5N1 and H5N6 in Vietnamese Live Bird Markets: Spatiotemporal Patterns of Distribution and Risk Factors. Front. Vet. Sci. 5:51. doi: 10.3389/fvets.2018.00051 comparative epidemiol...

The International Mouse Phenotyping Consortium (IMPC) is a major international effort to explore the effects of knocking out 20,000 genes in the mouse. A new study by White and colleagues, published in the current issue of Disease Models & Mechanisms, demonstrates the usefulness of lacZ in situ reporter expression patterns in extending our understanding of genotype-phenotype relationships as pa...

In this article we present a new type of 1D nanostructures consisting of supported hollow ZnO nanorods (NRs) decorated with Ag nanoparticles (NPs). The 3D reconstruction by high-angle annular dark field scanning transmission electron microscopy (HAADF-STEM) electron tomography reveals that the Ag NPs are distributed along the hollow interior of the ZnO NRs. Supported and vertically aligned Ag-N...

Oxidation of low density lipoproteins is an initial step of atherogenesis that generates pro-inflammatory phospholipids, including platelet-activating factor (PAF) and its analogs. PAF is degraded by PAFacetylhydrolase (PAF-AH), a circulating enzyme having both proand anti-inflammatory activities. PAF-AH activity has been postulated to be a risk factor for coronary artery disease (CAD); however...

Antibody drug conjugates are emerging as a powerful class of antitumor agents with efficacy across a range of cancers; therefore, understanding the disposition of this class of therapeutic is crucial. Reported here is a method of enriching a specific organelle (lysosome) to understand the catabolism of an anti-CD70 Ab-MCC-DM1, an antibody drug conjugate with a noncleavable linker. With such tec...