نتایج جستجو برای: ecf regimen
تعداد نتایج: 47070 فیلتر نتایج به سال:
background: gastric cancer is an important health problem across the world. chemotherapy in combination with local treatment is standard treatment for locally advanced gastroesophageal cancers. the purpose of this investigation was evaluation of response and tolerability to neoadjuvant eox regimen in locoregionally advanced gastric cancer. materials and methods: patients with locoregionally adv...
PURPOSE We report the results of a prospectively randomized study that compared the combination of epirubicin, cisplatin, and protracted venous infusion fluorouracil (5-FU) (ECF regimen) with the standard combination of 5-FU, doxorubicin, and methotrexate (FAMTX) in previously untreated patients with advanced esophagogastric cancer. PATIENTS AND METHODS Two hundred seventy-four patients with ...
Gastric cancer remains a significant problem in terms of global health, and is the most common cancer in Korea. Surgery is the only potentially curative treatment for localized gastric cancer, but most cases present at an advanced stage. Randomized trials have demonstrated that chemotherapy for advanced gastric cancer improves the quality of life and extends survival, by 4 approximately 6 month...
BACKGROUND A regimen of epirubicin, cisplatin, and infused fluorouracil (ECF) improves survival among patients with incurable locally advanced or metastatic gastric adenocarcinoma. We assessed whether the addition of a perioperative regimen of ECF to surgery improves outcomes among patients with potentially curable gastric cancer. METHODS We randomly assigned patients with resectable adenocar...
Globally, gastric and esophageal cancers are, respectively, the 2nd and 6th most common causes of cancer-related deaths; they are also an important cause of cancer-related morbidity 1. Surgical resection remains the definitive curative treatment for earlystage disease; however, most patients present with inoperable or metastatic disease. Consequently, overall 5-year survival rates are in the ra...
A new combined gas chromatography and mass spectrometry (GC-MS) method has been developed suitable for the urine sample treatment in aqueous phase with ethyl chloroformate (ECF) derivatization agents. The method has been extensively optimized and validated over a broad range of different compounds and urine samples. Analysis of test metabolite derivatives, containing spiked standards, or rat ur...
QUESTION What is the optimal chemotherapy regimen in advanced gastric cancer? PERSPECTIVES Gastric cancer is the second leading cause of cancer mortality worldwide. Despite low incidence rates for gastric cancer in Ontario, the overall prognosis is bleak, with 5-year survival rates of approximately 23% in Canada. Even with the considerable body of research available on chemotherapy for advanc...
East Coast fever (ECF) is a lymphoproliferative disease caused by the tick-transmitted protozoan parasite Theileria parva. ECF is one of the most serious cattle tick-borne diseases in Sub-Saharan Africa. We have previously demonstrated that three doses of the C-terminal part of the sporozoite protein p67 (p67C) adjuvanted with ISA206VG confers partial protection against ECF at a herd level. We ...
• Gastric and oesophageal cancer are the fifth and ninth most common cancers in the UK – audit data from English Cancer Registries show that in 2005 there were 4680 patients diagnosed with gastric cancer and 6375 diagnosed with oesophageal cancer. Most patients present with advanced, inoperable or metastatic disease – in 2005 only 20% of patients that presented with this disease underwent surgi...
Background In patients with resectable gastric or lower oesophageal adenocarcinomas the perioperative regimen of ECF (epirubicin, cisplatin, fluorouracil) has been proven to down-stage and significantly improve progression-free survival (PFS) and overall survival (OS) compared with surgery alone. This treatment has been applied in our centre since 2007. This is a retrospective audit to review a...
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