Pseudomonas aeruginosa PAO mutants defective in elastase were isolated by plate assays of nitrosoguanidine-mutagenized clones. A total of 75 elastase mutants were isolated from 43,000 mutagenized clones. One mutant (PAO-E64) was apparently identical to the parental strain except for its deficiency in elastase activity. This mutant produced an enzyme which was antigenically indistinguishable fro...

Malarial hemozoin may play an important role as a target for antimalarial drugs and in disease pathogenesis. A new assay for hemozoin was developed in which the hemozoin was separated from cells by filtration. Trophozoites have substantially more hemozoin than rings, but there are relatively small differences between chloroquine-sensitive and chloroquine-resistant strains. The effects of hemozo...

Potential new targets for antimalarial chemotherapy include parasite proteases, which are required for several cellular functions during the Plasmodium falciparum life cycle. Four new derivatives of N-alkyl and N-benzyl-1,10-phenanthroline have been synthesized. Those are (1)-N-methyl-1,10-phenanthrolinium sulfate, (1)-N-ethyl-1,10-phenanthrolinium sulfate, (1)-N-benzyl-1,10-phenanthrolinium ch...

Corrections are made to the names of the first two authors in Yohei, Kazuya & Mizuguchi [Acta Cryst. (2008), E64, m240-m241].[This corrects the article DOI: 10.1107/S1600536807066895.].

The chemical name in the title of the paper by Meng, Liu & Chen [Acta Cryst. (2008), E64, m106] is corrected.[This corrects the article DOI: 10.1107/S1600536807062903.].

The chemical name of the title compound in the paper by Kia, Fun & Kargar [Acta Cryst. (2009), E64, o2406] is corrected.[This corrects the article DOI: 10.1107/S1600536809023320.].

The formula of the title compound in the paper by Xu & Hu [Acta Cryst. (2008), E64, o1432] is corrected.[This corrects the article DOI: 10.1107/S1600536808020199.].

The title of the paper by Friedrich, Maguire, Martincigh, McKay & Pietersen [Acta Cryst. (2008), E64, m1240] is corrected.[This corrects the article DOI: 10.1107/S1600536808027943.].

The title of the paper by Mo, Hu, Chen, Yuan & Pan [Acta Cryst. (2008), E64, m391] is corrected.[This corrects the article DOI: 10.1107/S160053680801711X.].