Epithelial-mesenchymal transition (EMT) in epithelial cells has been indicated as an important component of neoplastic transformation although, the genetic mechanism involved in this process has not been defined. The aim of this study was to evaluate the expression of different genes related to EMT such as E-cadherin, TGFbeta1, TGFbeta2, h-RAS, TWIST1, SNAIL2, SMAD5, FN1, CEACAM1 and JAG1 using...

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We studied the proton-rich $T_z=-1$ nucleus $^{70}$Kr through inelastic scattering at intermediate energies in order to extract reduced transition probability, $B(E2;\;0^+ \rightarrow 2^+)$. Comparison with other members of $A=70$ isospin triplet, $^{70}$Br and $^{70}$Se, same experiment, shows a $3\sigma$ deviation from expected linearity electromagnetic matrix elements as function $T_z$. At p...

We studied the proton-rich $T_z=-1$ nucleus $^{70}$Kr through inelastic scattering at intermediate energies in order to extract reduced transition probability, $B(E2;\;0^+ \rightarrow 2^+)$. Comparison with other members of $A=70$ isospin triplet, $^{70}$Br and $^{70}$Se, same experiment, shows a $3\sigma$ deviation from expected linearity electromagnetic matrix elements as function $T_z$. At p...

The spreading of viral RNA within Swiss Albino mice orally inoculated with coxsackievirus B4 E2 strain (CVB4 E2) was studied by using RT-PCR and semi-nested-RT-PCR methods. Viral RNA was detected in various organs: pancreas, heart, small intestine, spleen, thymus, and blood at various postinfectious (p.i.) times ranging from 8 hr to 150 days. Our results show that (i) outbred mice can be infect...

The impact of estrogen on brain function, especially in individuals with diabetes, remains uncertain. This study aims to compare cerebral glucose metabolism levels intact rats, ovariectomized (OVX) and 17β-estradiol (E2)-treated OVX diabetic female rats. Sixteen rats were administered a single intraperitoneal injection 70 mg/kg streptozotocin (STZ) induce diabetes (intact, n = 6; OVX, OVX+E2-tr...

background: it is reasonable to think that some biochemical characteristics of follicular fluid (ff) surrounding the oocyte may play a critical role in determining the quality of oocyte and the subsequent potential needed to achieve fertilization and embryo development. objective: this study was carried out to evaluate the levels of ff homocysteine (hcy) in ivf candidate polycystic ovary syndro...

OBJECTIVES We assessed the responsiveness of salivary progesterone (P4) and estradiol (E2) to father-child interaction, including testing for differences in short-term hormonal change based on paternal characteristics. We also predicted that P4 exposure during the study period would relate positively to post-interaction paternal mood. METHODS We conducted an in-home intervention study in whic...

Both known estrogen receptors, ERalpha and ERbeta, are expressed in blood vessels. To gain further insight into the role of ERalpha in a functional setting, we investigated the effect of the novel highly selective ERalpha agonist Cpd1471 on vascular reactivity in ovariectomized spontaneously hypertensive rats (SHR). After ovariectomy or sham operation, 12-week-old female SHR received either 17b...