DNA coding for the core antigen from hepatitis B Virus (HBcAg) was amplified, cloned and propagated in E. coli. The core protein was expressed in E. coli and the product was readily detected by Western blot. This protein can be used as a diagnostic material in serum screening tests. To increase the level of expression of this antigen in bacteria, two plasmids were constructed in which the gene ...

Abstract BACKGROUND: Diagnosis of Echinococcus granulosus in the definitive host particularly in dog is the significant complication in the endemic area. OBJECTIVES: The aim of this study is serological detection of E. granulosus in the infected dogs. METHODS: Dot-ELISA based on the copro-antigen and recombinant EPC1 antigen (rEPC1) for antibody detection was performed. Blood and fecal samples ...

background: human leukocyte antigen-e (hla-e)is a non-classical major histocompatibility complex (mhc) class i antigens which expressed on extra villous cytotrophoblast, which interacts with nkg2a, is an inhibitory receptor on natural killer (nk) cells and leading to down regulation of immune response in the maternal-fetal interface and provides maternal immune tolerance of the fetus. objective...

background: cervical cancer is one of the most common types of women’s reproductive cancers. a major risk factor for cervical cancer is exposure to a group of common sexually transmitted viruses called human papillomavirus  (hpv). the over expression of hpv 16 i.e., e6 antigen in the tumors of suspected cervical cancer tissues. however e-6 antigen has hyaluronan binding protein site. methods: t...

Objective(s): The Botulism syndrome is caused by types A to G of botulinum neurotoxins. The binding domains of these neurotoxins are immunogenic and considered as appropriate candidate vaccines. Due to the low immunogenicity of recombinant vaccines, there have been many studies on the use of biocompatible carriers such as chitosan nanoparticles for the delivery of these vaccines. The aim of thi...

dna coding for the core antigen from hepatitis b virus (hbcag) was amplified, cloned and propagated in e. coli. the core protein was expressed in e. coli and the product was readily detected by western blot. this protein can be used as a diagnostic material in serum screening tests. to increase the level of expression of this antigen in bacteria, two plasmids were constructed in which the gene ...

Background: E-cadherin is a trans-membrane glycoprotein that plays a critical role in many aspects of cell adhesion as well as establishment and maintenance of epithelial cell polarity. Loss of the adhesive function of E-cadherin seems to promote invasive and metastatic properties of neoplastic cells. Objectives: The present study is a retrospective study aiming to evaluate the loss of E-cadher...

background: pediatric bronchial asthma is associated with considerable morbidity. the study was carried out to examine the association of human leukocyte antigen (hla)- class ii with the disease as we found no similar study on asian indian population. objective: to define the hla-class ii antigens in asian indian pediatric patients with asthma. methods: a total of 103 children with asthma and 1...