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lhermitte - duclos disease also called dysplastic gangliocytoma of cerebellum is an extremely rare cerebellar lesion which share features of both malformation and neoplasm. the usual presentation is of raised intracranial pressure along with cerebellar signs. we report a case of 23 year male who presented with headache & diplopia. mri was suggestive of the diagnosis. subtotal excision of th...

We report a rare case of dysplastic cerebellar gangliocytoma also called as Lhermitte-Duclos Disease located in the cerebellum in a young male without any neurological signs. Morphologically dysplastic neurons and immunohistochemical staining with neuronal and glial markers was all diagnostic on pathology. Also a non-enhancing cerebellar hemispheric mass with a striated pattern of hyper-, and i...

Lhermitte - Duclos disease also called dysplastic gangliocytoma of cerebellum is an extremely rare cerebellar lesion which share features of both malformation and neoplasm. The usual presentation is of raised intracranial pressure along with cerebellar signs. We report a case of 23 year male who presented with headache & diplopia. MRI was suggestive of the diagnosis. Subtotal excision of th...

Lhermitte-Duclos disease, also known as dysplastic cerebellar gangliocytoma, was first diagnosed by doctors Lhermitte and Duclos in 1920. In subsequent years, the disease was described by many researchers: Bielschowsky and Simons in 1930, Christensen in 1937, Duncan and Snodgrass in 1943, Ambler in 1969, and Padber in 1991. Each of the authors referred to this disease in a different way: diffus...

Lhermitte-Duclos disease (LDD) is a benign neoplasm of posterior fossa, involving cerebellum. It is also known as dysplastic cerebellar gangliocytoma. It is not a true neoplasm but a hamartoma. It can be either isolated finding or associated with Cowden (multiple hamartoma syndrome). adults.

Lhermitte-Duclos disease was first described in 1920 in the literature under the names of Purkinjeoma, granular cell hypertrophy of the cerebellum, hamartoma of the cerebellum, dysplastic gangliocytoma, ganglioneuroma, and gangliomatosis of the cerebellum. Patients tend to be young adults and may present with signs of cerebellar dysfunction or increased intracranial pressure secondary to obstru...