introduction: 5-ht1a receptor is related with a variety of neuropsychiatric disorders. . in this study a phenolic analogue derived from dway [desmethyl way-100635 (n-(2-(1-(4-(2-methoxyphenyl)piperazinyl)-ethyl))-n-(2-pyridinyl) cyclohexanecarboxamide)] is used to design the desired structure of 5-ht1a receptor imaging agents after labeling with [99mtc (co) 3(h2o) 3] + core via dithiocarbamate ...

x.doi.org/10.10 66//& 2016 E ent of Orthop York, NY. reprint reque opaedic Surg dway, Suite 8 mbia.edu The treatment of early-onset scoliosis (EOS) has evolved substantially over the years. Traditional growing-rod constructs rely on spine-based fixation for proximal and distal anchor sites. Hybrid growing-rod constructs pair rib-based proximal anchors with spinal or pelvic anchors distally. Bot...

[Carbonyl-(11)C]WAY-100635 (WAY) has proved to be a very useful radioligand for the imaging of brain 5-HT(1A) receptors in human brain in vivo with positron emission tomography (PET). WAY is now being applied widely for clinical research and drug development. However, WAY is rapidly cleared from plasma and is also rapidly metabolised. A comparable radioligand, with a higher and more sustained d...

Introduction: 5-HT1A receptor is related with a variety of neuropsychiatric disorders. . In this study a phenolic analogue derived from DWAY [Desmethyl WAY-100635 (N-(2-(1-(4-(2-methoxyphenyl)piperazinyl)-ethyl))-N-(2-pyridinyl) cyclohexanecarboxamide)] is used to design the desired structure of 5-HT1A receptor imaging agents after labeling with [99mTc (CO) 3(H2O) 3] + cor...