this review presents a brief outline of our current knowledge of the structure and chemical composition of the outer membrane vesicles (omvs), originating from the surface of gram negative bacteria including their outer membrane proteins and lipopolysaccharides. moreover, the functional roles and applications of omvs in medical research such as omv-based vaccines, omv adjuvants properties, omv ...

Our study investigates the incidence of children left unattended in parked motor vehicles in Brazil. These events have been widely explored in the United States but less so abroad, and never in Brazil. Over the period from 2006 to 2015, we collected data from news reports on 31 cases, including 21 fatalities. The circumstances mostly involved a caregiver, especially a parent, forgetting the chi...

Extracellular vesicles (EVs) are currently being considered as promising drug delivery vehicles. EVs are naturally occurring vesicles that exhibit many characteristics favorable to serve as drug delivery vehicles. In addition, EVs have inherent properties for treatment of cancers and other diseases. For research and clinical translation of use of EVs as drug delivery vehicles, in vivo tracking ...

To address the issue of safely accessing and securing wheeled mobility devices in motor vehicles, more information characterizing current-production devices was needed. In a recent effort, frame characteristics of wheeled mobility devices were defined and a database developed for recording characteristics relevant to access and securement. A representative number of devices have been surveyed t...

UNMIX and Positive Matrix Factorization (PMF) solutions to the Chemical Mass Balance (CMB) equations were applied to chemically speciated PM2.5 measurements from 23 sites in California's San Joaquin Valley to estimate source contributions. Six and seven factors were determined by UNMIX for the low_PM2.5 period (February to October) and high_PM2.5 period (November to January), respectively. PMF ...

Amphiphilic block copolymer micelles have been the focus of research for the last decades because of the promising properties as nano size drug delivery vehicles. In polar aqueous milieu, copolymers self assemble into micelle structures which consist of hydrophilic corona and hydrophobic core regions. Space created inside the micelle core can be used for transportation of drug molecules of hydr...

Non-aqueous system are well known as solvent or drug suspension vehicles and oleogels micro emulsion with no aqueous phase (anhydrous, non-aqueous oil-in-oil emulsion) have had relatively scant attention yet may have uses as drug reservoir as well as template for the preparation of microemulsion combination with a cosurfactant. Microemulsions have emerged as novel vehicles for drug delivery whi...

A better understanding of the risk involved in riding different sizes and types of motor vehicles is required to make informed decisions regarding a reasonable level of protection for wheelchair riders. Wheelchair rider accident information that can be used to estimate risk is quite limited. This paper reviewed the resources available, including the National Electronic Injury Surveillance Syste...