In this paper, a bi-objective pharmaceutical supply chain network under uncertainty demand and transportation costs is modeled and developed. To control the uncertainty parameters, the robust optimization method is considering. The main objective of this paper determines the number and location of potential facilities such as drug manufacture centers and drug distribution centers by considering...

We consider inventory systems of “perishable” goods. Perishable goods cannot be carried from one period to another. Examples of perishable goods include newspaper, Christmas tree, and many grocery items like milk and banana. Here, a period could be one day, or one week, or any time frame that is appropriate in the application context. Suppose that a retailer sells a particular perishable produc...

An Economic Lot-sizing(ELS) problem with perishable inventory has been studied extensively over the years and plays a fundamental role in the inventory management. In this paper, we consider the problem where backlogging is allowed with the general economies of scale cost functions. Since the special case without backlogging is NP-hard, the considered problem is also NP-hard. The main contribut...

This paper studies a perishable inventory model, which assumes that each perishable item has finite lifetime, and only one item is consumed each time. The lifetimes of perishable items are independent random variables with the general distribution and so are the consumption internal. Under this assumption, by using backward equations and limit distribution of Markov skeleton processes, this pap...

Abstract Assume that customers are price sensitive, changes in the price of perishable products will bring changes in demand, and business can adjust the perishable products' price to influence the market demand, a perishable products multi-stage pricing model considering cancelations and no-shows is proposed, and the optimal pricing, the optimal expected revenue with the products' initial quan...

This study has extended a vehicle routing problem, with time-windows (VRPTW), by considering the randomness of the perishable food delivery process, and constructing a SVRPTWmodel, to obtain optimal delivery routes, loads, fleet dispatching and departure times for delivering perishable food from a distribution center. Our objective was to minimize not only the fixed costs for dispatching vehicl...

If a monopoly supplies a perishable good, such as tickets to a performance, and is unable to price discriminate within a period, the monopoly may benefit from the potential entry of resellers. If the monopoly attempts to intertemporally price discriminate, the equilibrium in the game among buyers is indeterminate when the resellers are not allowed to enter, and the monopoly’s problem is not wel...

The incorporation of database technology into hard real-time systems presents an important but difficult challenge to any system designer. Notions of consistency and failure atomicity are attractive for architects of dependable hard real-time applications. Unfortunately the hard real-time requirements of bounded access times are not easily imposed upon the concurrency control methods usually fo...

We study a supply chain network equilibrium model for perishable products under the theory of discrete choice models, which comprises multiple perishable product manufacturers, distributors and retailers. Our goal is to present equilibrium outputs for different firms in this supply chain network model for perishable products based on retailers’ utility maximization. The network model is built u...

This article addresses a general tri-objective two-echelon capacitated vehicle routing problem (2E-CVRP) to minimize the total travel cost, customers waiting times and carbon dioxide emissions simultaneously in distributing perishable products. In distributing perishable products, customers’ satisfaction is very important and is inversely proportional to the customers waiting times. The propose...