background: poisoning with non-barbiturate anti-epileptics (carbamazepine, sodium valproate and phenytoin) shows a growing trend. the objective of this study was to investigate clinical manifestations of poisoned patients with these medications. methods: this prospective study was conducted in the shiraz shoushtari hospital during a two-year period from 2010 to 2012. poisoning was confirmed acc...

background:every day, people with addiction cause heavy economic and cultural damage to society. in some circumstances, opioids are used as a tool for suicide, which is often seen in youth. the aim of this study was to investigate the clinical signs of toxicity associated with opium in patients referred to ardabil city hospital. methods:this is a cross-sectional study that has been done on opiu...

AIMS Accidental drug overdose contributes substantially to mortality among drug users. Multi-drug use has been documented as a key risk factor in overdose and overdose mortality in several studies. This study investigated the contribution of multiple drug combinations to overdose mortality trends. DESIGN We collected data on all overdose deaths in New York City between 1990 and 1998 using rec...

Drug overdose deaths in the United States are a pressing public health challenge (1–3). In particular, drug overdoses involving opioids have increased since 1999 (1). This report focuses specifically on drug overdose deaths for older adolescents aged 15–19. In 2015, 772 drug overdose deaths occurred in this age group. Rates for 1999–2015 are presented and trends compared for both females and ma...

BACKGROUND Although previous studies have identified high levels of drug-related harm in Thailand, little is known about illicit drug overdose experiences among Thai drug users. We sought to investigate non-fatal overdose experiences and responses to overdose among a community-recruited sample of injection drug users (IDU) in Bangkok, Thailand. METHODS Data for these analyses came from IDU pa...

The distribution of naloxone to heroin users is a suggested intervention to reduce overdose and death rates. However, the level of willingness of drug users to administer this medication to others is unclear. Drug users recruited from the community between January 2002 and January 2004 completed a structured interview that assessed topics including drug use, overdose history, and attitudes towa...

AIMS To estimate the extent and nature of overdose and factors associated with overdose among injecting drug users in London. DESIGN Three hundred and twelve current injecting drug users were recruited and interviewed in community settings by a team of "privileged access interviewers". MEASUREMENTS A structured questionnaire was used that covered the following areas: demographic characteris...

BACKGROUND Drug overdose is an important, yet an inadequately understood, public health problem. Global attention to unintentional drug overdose has been limited by comparison with the scope of the problem. There has been a substantial increase in drug overdose incidence and prevalence in several countries worldwide over the past decade, contributing to both increased costs and mortality. OBJ...

AIMS To determine the contribution of heroin, prescription opioids, cocaine and alcohol/drug combinations to the total overdose death rate and identify changes in drug overdose patterns among New Mexico subpopulations. DESIGN We analyzed medical examiner data for all unintentional drug overdose deaths in New Mexico during 1990-2005. Age-adjusted drug overdose death rates were calculated by se...

BACKGROUND Medication overdose accounts for >80% of hospital presentations for self-harm. Previous research has identified typical characteristics of medication overdose cases; however, these cases have not been well differentiated from other similar presentations, namely (1) illicit drug overdose and (2) self-harm by means other than overdose. METHOD A 12-month audit of medication overdose c...