نتایج جستجو برای: drug hypersensitivities
تعداد نتایج: 589809 فیلتر نتایج به سال:
results: a total number of 117 patients were evaluated for adverse drug reactions, among them, 97 (82.9%) were considered to have immunological drug reactions. the most common symptoms of allergic drug reactions were morbilliform eruptions, serum sickness, dress (drug rash with eosinophilia and systemic symptoms), and toxic epidermal necrolysis. in 62 patients, anticonvulsant drugs had the prom...
Hypersensitivity reactions are classified into four groups (Type I, II, III, and IV), each characterized by specific biological actions. Research has focused on understanding each hypersensitvity to ensure appropriate therapeutic recommendations are made. This overview will present the defining characteristics of each hypersensitivity and examine the diagnostic methods used to determine the exi...
Idiosyncratic adverse drug reactions are unpredictable, dose-independent and potentially life threatening; this makes them a major factor contributing to the cost and uncertainty of drug development. Clinical data suggest that many such reactions involve immune mechanisms, and genetic association studies have identified strong linkages between drug hypersensitivity reactions to several drugs an...
Patients with Sjogren's syndrome (SS) frequently have irritable bowel like symptoms (IBS). Some have celiac sprue. The current studies were designed to examine the presence of food hypersensitivities in a population of patients with SS and IBS. Ten patients were selected from the autoimmune disease clinics at SUNY at Buffalo who had SS and IBS symptoms. Food hypersensitivities were determined b...
Auditory hypersensitivities are a common feature of autism spectrum disorder (ASD). In the present study, the effectiveness of a novel intervention, the listening project protocol (LPP), was evaluated in two trials conducted with children diagnosed with ASD. LPP was developed to reduce auditory hypersensitivities. LPP is based on a theoretical "neural exercise" model that uses computer altered ...
Background Allergic reactions to drugs are often unpredictable and can lead to serious side effects such as anaphylactic shock. According to the hapten hypothesis, any drug with a molecular weight lower than 1000 daltons cannot induce an immune response by itself and must be bound to a protein. Antigen presenting cells, such as dendritic cells (DC), internalize hapten-protein conjugates and dig...
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