results anxiety, as the second most common reason of psychiatric disorders in cases of poisoning, with a prevalence of 12.1% in form of mild, 75.9% moderate and 12.1% severe, was confirmed among the participants of this study. conclusions the prevalence of anxiety among cases of poisoning with both drugs and chemicals are noticeably higher than general population. this fact strongly suggests th...

background: restless and violent behaviors are common in emergency departments (eds), which need therapeutic interventions in most of the times. the first-generation anti-psychotic drugs are one of the most applicable therapeutic agents in the management of such patients, but their use has some limitations. some studies suggest midazolam as an alternative medicine. therefore, this study was per...

hepatic toxicity is the most serious adverse effect of anti tuberculosis drugs. this study was performed to evaluate efficacy of silymarin as a hepatoprotective herbal agent. in a randomized double blind clinical trial 70 new cases of pulmonary tuberculosis were divided into two groups. the intervention group was assigned to receive silymarin and the control group received placebo. tuberculosis...

background: renal failure is an important adverse effect of drug poisoning. determining the prevalence and etiology of this serious side effect could help us find appropriate strategies for the prevention of renal failure in most affected patients. objectives: the present study is aimed to identify drugs that induce renal failure and also to find the prevalence of renal failure in patients refe...

neuroleptic malignant syndrome (nms) is a rare but life-threatening idiosyncratic side effect resulting from neuroleptic drugs. nms mainly occurs in patients treated with high-potency typical antipsychotics, but rarely caused by atypical antipsychotics. although nms is less common with atypical antipsychotic, but it seems that its incidence is rising due to increased administration of such drug...

patients and methods this cross-sectional study on 71 patients with ms was carried out between 2010 and 2012, in an iranian population. demographic and pharmacological variables were recorded in d-base. statistical analyses were performed using spss for windows. results the females/males sex ratio within the study population was 3.17: 1. the mean age of females was 32.2 years old (range 20 - 45...

objective: the protective effect of silymarin (smn) on mycophenolate mofetil (mmf)–induced duodenal disorders was investigated. materials and methods: forty-two wistar rats were assigned to seven groups including control and test groups. the control animals received saline and the test animals were treated with mmf (30 mg/kg, orally) and saline, mmf and smn (25, 50, and 100 mg/kg, orally), mmf ...

Acute myopia following use of some drugs is a relatively rare condition. Topiramate prescribed for seizure prophylaxis is one of these drugs. In this paper a case of acute transient myopia after taking topiramate is reported. The reported patient is a 28-year old woman who had no history of any eye disease. Following consumption of topiramate pill for one week, she had found blurred vision ...