background: leishmaniases are a group of diseases caused by leishmania parasites .  growing of drug unresponsiveness in leishmaniasis patients necessitates the development of new drugs and accor­dingly a suitable assay is needed for evaluation of any modalities.  the aim of this study was to compare four drug assays methods, agar dilution, broth dilution, cylinder plate and disk diffusion, for ...

A pharmacokinetic study was set up to investigate the pharmacokinetics of anti-emetic agents aprepitant and dexamethasone drug-drug interaction between these drugs in children. In order quantify dexamethasone, a liquid chromatography-tandem mass spectrometry assay developed validated for simultaneous analysis dexamethasone. Protein precipitation with acetonitrile-methanol (1:1, v/v) used extrac...

background :wide distribution and low half-life of acyclovir has led to a high dose consumption of the drug. recent studies have shown that encapsulation of acyclovir in nano-carriers can increase effectiveness and decrease its side effects. we investigated the inhibitory effect of acyclovir loaded nano-niosomes against herpes simplex virus type-1 (hsv-1) in cell culture.   methods : in-vitro c...