Cefepime is a fourth-generation cephalosporin which is approved in Europe and in the USA. Food and Drug Administration (FDA) approves cefepime in the treatment of febrile neutropenia. Cefepime is active against gram-negative microorganisms such as Escherichia coli, Haemophilus influenzae, Enterobacter, Klebsiella, Morganella, Neisseria, Serratia, and Proteus species. Cefepime is also active aga...

purpose: propofol is one of the most common drugs used in anesthesia induction and the pain during its intravenous injection is one of the most important side effectsthat it has. therefore, many methods and drugs have been examined so far to reduce or eliminate this side effect. in this study a lot the effects of alfentanil, magnesium sulfate and ketamine drugs on reducing the pain during intra...

Gene/genome dosage balance is an essential evolutionary mechanism for organisms to ensure a normal function, but the underlying causes of dosage-imbalance regulation remain poorly understood. Herein, the serial Brassica hybrids/polyploids (AC, AAC, CCA, CCAA) with different copies of A and C subgenomes from the same two parents of Brassica rapa and Brassica oleracea were synthesized to investig...

Retrospective voting studies typically examine policies where the public has common interests. By contrast, climate policy has broad public support but concentrated opposition in communities where costs are imposed. This spatial distribution of weak supporters and strong, local opponents mirrors opposition to other policies with diffuse public benefits and concentrated local costs. I use a natu...

OBJECTIVE To compare the effects and side effects of low dosage tricyclic antidepressants with placebo and with standard dosage tricyclics in acute phase treatment of depression. DESIGN Systematic review of randomised trials comparing low dosage tricyclics (< or =100 mg/day) with placebo or with standard dosage tricyclics in adults with depression. MAIN OUTCOME MEASURES Relative risk of res...

Recently, we proposed an autoregressive linear mixed effects model for the analysis of longitudinal data in which the current response is regressed on the previous response, fixed effects, and random effects (Funatogawa et al., Statist. Med. 2007; 26:2113-2130). The model represents profiles approaching random equilibriums. Because intermittent missing is an inherent problem of the autoregressi...