BACKGROUND The geographic map of cancer prevalence differs due to environmental and dietary factors in various populations. High prevalence of a number of cancers in some regions is thought to be attributed to local dietary habits. Dorema aucheri (Bilhar) is used commonly as an herbal medicine in some regions including Iran. The aim of this study was to evaluate whether Dorema aucheri has carci...

Dear Editor, Seven species have been reported in the genus Dorema, family Umbelliferae, in the flora of Iran, among which two are endemic: D. aucheri Boiss. and D. ammoniacum D. Don. 1 In Iranian traditional medicine, Dorema aucheri has been employed as stimulant, nervonic, antispasmodic, bronchodilator, expectorant, kidney stone repellent, emmenagogue and analgesic for visceral pain. This plan...

OBJECTIVES The present study investigated the antidiabetic and hypolipidemic properties of Dorema aucheri leave hydroalcoholic extract in nicotinamide-streptozotocin induced type 2 diabetic rats. MATERIALS AND METHODS nicotinamide/streptozotocin-induced diabetic rats were supplemented orally with three different doses of D. aucheri (100, 200 and 400 mg/kg BW) or glibenclamide (0.25 mg/kg) for...

BACKGROUND Dorema aucheri is a plant of Apiaceae family which is used widely in some states of Iran. Different extracts and essential oil of Dorema species contain flavonoids and cumarin compounds which have anti-hypertensive, cholesterol- and triglycerides-lowering properties. This study was undertaken to evaluate the genotoxic properties of hydroalcoholic and aqueous extracts of D. aucheri on...

most serious problem that leads to reproductive system failure in both human and animals. Present study was carried out to investigate whether hydroalcholic extract of Dorema aucheri leaves could protect the male rats against lead-induced reproductive toxicity. Materials and Methods: Adult wistar rats were treated with 0.1% lead acetate in drinking water with or without 100, 200 and 400 mg/kg D...

objective(s):the present study investigated the antidiabetic and hypolipidemic properties of dorema aucheri leave hydroalcoholic extract in nicotinamide-streptozotocin induced type 2 diabetic rats. materials and methods: nicotinamide/streptozotocin-induced diabetic rats were supplemented orally with three different doses of d.  aucheri (100, 200 and 400 mg/kg bw) or glibenclamide (0.25 mg/kg) f...

Elevated serum cholesterol and triglyceride is well established as a risk factor development of arteriosclerosis and coronary heart disease. A number of clinical studies have shown that reducing elevated levels of serum cholesterol and triglyceride, by drugs or dietary intervention, could lead to reduction in the incidence of coronary-related deaths. The search for new drug with the potential t...

Elevated serum cholesterol and triglyceride is well established as a risk factor development of arteriosclerosis and coronary heart disease. A number of clinical studies have shown that reducing elevated levels of serum cholesterol and triglyceride, by drugs or dietary intervention, could lead to reduction in the incidence of coronary-related deaths. The search for new drug with the potential t...

dorema aucheri boiss. (apiaceae) is an endemic plant growing in iran. this plant is used as food and its extracts are recommended for the treatment of a wide range of diseases. to conduct this study, leaf, stem, and flower of d. aucheri were collected from near yasouje, iran. antioxidant and antimicrobialeffects of methanol extracts were measured. further, total phenolic,flavonoid, anthocyanin,...