in this study, the influence of dopamine receptor agonists and antagonists on antinociception induced by bac10fen has been examined in the formalin test. the gaba-b agonist bac10fen induced antinociception in both phases of the formalin test in mice. the dopamine receptor agonists skf 38393 and quinpirole also induced antinociception in both phases of the test. skf 38393 but not quinpirole pote...

there is interrelationship between the immune and nervous systems that is accomplished by the molecular mediators. dopamine is one of the most important neurotransmitters. five different dopamine receptor genes (drd1, drd2, drd3, drd4, and drd5) have been recognized and cloned. the expression of the dopamine receptors is well characterized in the brain but little work has been done to examine t...

because of participation in many aspects of human life, and due to oxidation-sensitive characteristics of dopamine (da) and arachidonoyl dopamine (aa-da), the necessity of biocompatible carrier to keep them against oxidation is of importance. in this work, we explored the putative binding sites of da and aa-da to -lactoglobulin (blg) as potent carrier. docking results identified the binding si...

Background: Feeding behavior is regulated by a complex network which interacts via diverse signals from central and peripheral tissues. It is known dopaminergic and glutamatergic systems have crucial role on food intake regulation but scarce reports exist on their interaction in appetite regulation in broilers. OBJECTIVES: The present study was designed to examine the role of glutamatergic syst...

Dopamine is a neuromodulator and neurotransmitter responsible for number of physiological processes. Dysfunctions the dopamine metabolism signalling are associated with neurological psychiatric diseases. Here we report that in primary co-culture neurons astrocytes dopamine-induces calcium signal suppress spontaneous synchronous oscillations (SSCO) neurons. Effect on SSCO was dependent could be ...

objective(s): the dopamine level of the nucleus accumbens changes during some stereotyped behaviors. to study dopamine level of the nucleus accumbens in intra infralimbic apomorphine-induced climbing, microdialysis probes were implanted into the nucleus accumbens shell of male sprague dawley rats weighting 275–400 g.   materials and methods: the rats were divided into two groups (apomorphine an...

  Objective(s): The dopamine level of the nucleus accumbens changes during some stereotyped behaviors. To study dopamine level of the nucleus accumbens in intra infralimbic apomorphine-induced climbing, microdialysis probes were implanted into the nucleus accumbens shell of male Sprague Dawley rats weighting 275–400 g.   Materials and Methods: The rats were divided into two groups (apomorphine ...

In this study, the influence of dopamine receptor agonists and antagonists on antinociception induced by bac10fen has been examined in the formalin test. The GABA-B agonist bac10fen induced antinociception in both phases of the formalin test in mice. The dopamine receptor agonists SKF 38393 and quinpirole also induced antinociception in both phases of the test. SKF 38393 but not quinpirole ...

A simple approach based on cyclic voltammetry (CV) was developed for the simultaneous determination of dopamine (DA) and uric acid (UA) in the presence of ascorbic acid (AA) using a modified glassy carbon paste electrode (GCPE). In the present study, analytical parameters were optimized and electrochemical performance of modified electrode was investigated. The calibration curves were obtained ...

objective: the present study aimed to review the relapse rate in patients with schizophrenia treated with orally taken atypical agents (serotonin dopamine antagonists, sdas) and depot preparation of conventional (typical) antipsychotics. methods: in this historical cohort study, mean relapse per month (mrm) index, duration between initiation of antipsychotic treatment and the first relapse epis...