purpose: to determine bacterial contamination of corneas and corneal storage media provided from the eye bank of i.r. iran to rasool akram medical center. methods: this descriptive study was performed on 70 corneoscleral rims and corneal storage media. one milliliter of corneal storage media and the corneoscleral rim were sent to microbiology laboratory at the time of penetrating keratoplasty a...

PURPOSE The purpose of this study was to assess the relationship between donor factors and 5-year corneal graft survival in the Cornea Donor Study. METHODS Donor corneas met criteria established by the Eye Bank Association of America, had an endothelial cell density of 2300 to 3300/mm, and were determined to be of good to excellent quality by the eye banks. Donor corneas were assigned using a...

purposes: to report a case of primary graft failure (pgf) and systemic manifestations of herpes simplex virus (hsv) infection following transplantation of an hsv-contaminated donor cornea. patient and findings: a 28-year-old male with history of penetrating keratoplasty 12 days before, developed intraocular inflammation with marked anterior chamber reaction, graft edema and elevated intraocular...

PURPOSE The aim of this study was to describe the challenges in Descemet membrane endothelial keratoplasty (DMEK) donor preparations and provide new strategies to achieve success. METHODS A series of 263 consecutive DMEK preparation attempts by a novice surgeon during a corneal fellowship are described. In all cases, the Descemet membrane (DM) and the endothelium were peeled off from the dono...

Keratoconus (KC) is a bilateral sight threatening disease that affects the cornea. It consists of gradual steepening central cornea associated with irregular astigmatism and may lead to corneal opacities. In some cases, keratoplasty needed restore vision. Even though it not frequent, recurrence KC in donor tissue has been described, usually bilateral. Recurrence respond problems related graft o...

We developed cell-free implants, comprising carbodiimide crosslinked recombinant human collagen (RHC), to enable corneal regeneration by endogenous cell recruitment, to address the worldwide shortage of donor corneas. Patients were grafted with RHC implants. Over four years, the regenerated neo-corneas were stably integrated without rejection, without the long immunosuppression regime needed by...

PURPOSE To evaluate the intraoperative changes in the donor lenticule, recipient cornea, and the reduction of interface fluid thickness during Descemet's stripping and automated endothelial keratoplasty with EndoGlide™ (Angiotech Pharmaceuticals Inc, Vancouver, Canada) donor insertion, using intraoperative spectral-domain optical coherence tomography. METHODS Prospective observational case se...

purpose: to report the possible transmission of zygomycetes infection by a corneal graft harvested from a donor with signs of trauma to the orbital region to a keratoconic patient who underwent deep anterior lamellar keratoplasty (dalk). case report: a 19-year-old keratoconic man underwent dalk in the right eye. the corneal graft was harvested from a donor with signs of orbital trauma. on posto...