نتایج جستجو برای: dna interaction

تعداد نتایج: 1043558  

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه رازی - دانشکده علوم 1391

we have two part in this thesis, at first: the interaction of native calf thymus dna (ct-dna) with two anthraquinones including quinizarin (1,4- dihydroxy anthraquinone) and danthron (1,8- dihydroxy anthraquinone) in a mixture of 0.04 m brittone-robinson buffer and 50% of ethanol were studied at physiological ph by uv-vis absorption, florescence, circular dichroism spectroscopic methods, viscos...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه تبریز - دانشکده علوم طبیعی 1391

in recent years many researchers have been focused on interaction of small molecules with dna. dna is generally the primary intracellular of anticancer drugs, so the interaction between small molecules and dna can cause dna damage in cancer cells, blocking the division of cancer cells and resulting in cell death. the flavonoids are a large group of polyphenolic natural products that are widely ...

Journal: :gene, cell and tissue 0
seyedeh elham mostafavinia department of biochemistry, faculty of medicine, birjand university of medical sciences, birjand, ir iran reyhane hoshyar department of biochemistry, faculty of medicine, birjand university of medical sciences, birjand, ir iran; department of biochemistry, faculty of medicine, birjand university of medical sciences, birjand, ir iran

background some herbal anticancer agents have direct interactions with dna. objectives the present study aimed to investigate the interaction of ctdna with rosemary flowers. materials and methods we used uv-vis, fluorescence and circular dichroism (cd) spectroscopic techniques. results the absorption of dna at 260 nm increased on addition of rosemary. herb extract quench the fluorescence of etb...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه رازی - دانشکده علوم 1390

3,5,6-trichloro-2-pyridinol ) tcp) متابولیت پایدار دو آفت کش(tricloropyr و(clorpyrifos است. که این دو آفت کش در کشاورزی استفاده فراوانی دارند. در این مطالعه برهم کنش بین tcpبا dna وhsa درph فیزیولوژیک(=ph7.4( و در بافر تریس کلراید بررسی شده است. نوع اتصال dna به hsa با استفاده از تکنیک های cd,uv,cv, وژل الکتروفورز بررسی شد.در حضور dna طیف uv مربوط به tcpدارای افزایش بود.طیف cd مربوط به dna در ...

Journal: :journal of physical & theoretical chemistry 2009
b. ghalandari f. mollaamin l. pishkar b. khalili haddad

the interaction of biomolecules with carbon nanotubes (cnts) has generated a great deal ofinterest in the past few years. the interaction between b-form single-strand dna (ssdna) andsingle-walled carbon nanotubes (swcnts) is a subject of intense current interest; however thereare a relatively small number of papers in the literature dealing with interaction of dna andswcnts. in this work we inv...

Journal: :physical chemistry research 2014
ali haidar pakiari maryam farrokhnia

in the present study, the interactions of three different lithium species li+, li3+ and ch3li with several different sites of the most stable tautomers of dna nucleo-bases are presented. this investigation is based on the results of thermochemical properties, quantum theory of atoms in molecules (qtaim) and natural bond orbital (nbo) analysis, obtained at b3lyp/6-311++g(d,p) level of theory. th...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه یاسوج - دانشکده ادبیات و علوم انسانی 1392

an investigation into oral interaction in language classes: a conversation analytic point of view the aim of this thesis is to analyze the interaction between language teachers and students in english language institutes. this work is done in the context of yasuj city. learning another language, which is in most cases english, involves many variables. one of these variables is the linguistic...

In this study, the interaction of the anthracycline antibiotic doxorubicin with DNA-HMG 1 complex was investigated employing UV/VIS spectroscopy, thermal denaturation and DNA cellulose chromatography techniques. The results indicated that the binding of doxorubicin to the protein reduces its Tm in a dose dependent manner. Although doxorubicin protects free DNA against thermal denaturation ...

ژورنال: دانشور پزشکی 2011
حبیبی, زهره , حسن, زهیر محمد, حسنی, لیلا , مظفری, ولی‌اله , نوری, شکوفه , یوسفی-محمدی, مریم -مهدی ,

Background and Objective: To evaluate interaction of salvigenin with DNA and the molecular mechanism of its anti-cancer effect. Materials and Methods: Salvigenin from Tanacetum canescens and DNA from calf thymus were isolated and purified. Then, salvigenin interaction with DNA in Tris buffer (0.05 M, pH equal to 4.7 and the temperature at 25 °C) was studied by different methods. Results and Con...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه رازی - دانشکده علوم 1390

برهمکنش dnaتیموس گاوی طبیعی (ct-dna) با اتیلن دی آمین تترااستات (edta)در بافرtris-hcl با 8/7 ph ( دراین ph،edta به نمک دی سدیم تبدیل می شود) وسسامول در بافر tris-hcl با4/7 ph مورد بررسی قرار گرفته است. edta و سسامول استفاده فراوانی در تکنولوژی غذایی و صنعت شیمیایی دارند. مدل اتصال dna مربوط بهedta بوسیله اسپکتروفتومتری جذب، دورنگ نمایی حلقوی(cd)، ویسکومتری وژل الکتروفورز بررسی شده است. طیفuv ...

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