Candidiasis is defined as an infection or disease caused by a fungus of the genus Candida. Rate of disseminated candidiasis increases with the growth of the number of immunocompromised patients. In the the last few decades the incidence of disseminated candidiasis is in growth as well as the mortality rate. The aim of this survey is to show the importance of serological tests implementation in ...

the aim of this study was to investigate the immunomodulatory effects of spirulina platensis (s.platensis) by measuring the levels of serum interleukin (il)-4, il-10, il-17, tumor necrosis factor(tnf)-α and interferon (ifn)-|γ| in mice suffered from systemic candidiasis and breast cancer. theaqueous extract of s. platensis was selected for this study. balb/c female mice were inoculated withcand...

hepatosplenic candidiasis is a fungal infection, which mostly affects patientswith hematologic malignancies such as leukemia. the pathogenesis of thisinfection is not clear yet, and the liver is the most commonly affected organ.diagnosis of hepatosplenic candidiasis can be only established via biopsy,since computed tomography (ct) scan, ultrasonography, and magneticresonance imaging (mri) yield...

disseminated candidiasis is an opportunistic infection in immunosuppressed animals by candida species. the purposes of this study were to determine the predominant candidal forms in different tissues and tissue reactions. sixteen dogs were selected in this study. the treatment dogs were immunosuppressed by intravenous administration of cyclophosphamide and after 5 days, they were challenged wit...

We describe the phenomenon of waning of focal hepatic and/or splenic lesions on abdominal computed tomographic (CT) scan during neutropenia in patients with chronic disseminated candidiasis. After observation of the phenomenon in one patient, a total of five cases were prospectively monitored with serial CT scans. After the diagnosis of disseminated candidiasis, hepatic lesions decreased in siz...

We present a case of disseminated intracranial infection by Candida albicans in a 5-year-old girl who had fever and a change of consciousness after surgery for complex congenital heart malformation. MR imaging revealed multiple small ring-enhancing hemorrhagic abscesses. One year after antifungal treatment, the abscesses and ventriculomegaly were almost completely resolved. The patient was disc...

Although highly susceptible to orogastric candidiasis, T-cell receptor delta- and alpha-chain knockout mice, deficient in gammadelta and alphabeta T cells, respectively, were found to be resistant to disseminated candidiasis of endogenous origin and to acute systemic candidiasis (resulting from intravenous injection).

L-743,872 (M991), which is a pneumocandin derivative, was evaluated in a mouse model of disseminated candidiasis caused by a fluconazole-resistant isolate of Candida albicans. In immunocompetent mice M991 prolonged survival at doses as low as 0.0125 mg/kg of body weight per day. In neutropenic mice 0.05 mg/kg was the lowest effective dose. M991 is a very potent drug for treatment of disseminate...

C andida spp. have become leading causes of lethal bloodstream infections in countries with advanced medical technology [1]. It is generally and correctly understood that disseminated candidiasis is ‘‘an opportunistic infection’’ that does not occur in healthy people outside of hospitals. It is also incorrectly often said that most patients who develop disseminated candidiasis are ‘‘immunocompr...