fifteen broiler chickens (cobb 400) of 42 days of age weighing 1.8 to 2.0 kg were equally divided into 3 groups, each consisting of 5 birds. hepatopathy was induced by oral administration of paracetamol while nephropathy was induced by intravenous administration of uranyl nitrate. kinetic study was investigated in healthy, hepatopathic and nephropathic birds following single oral administration...

A model checking technique to specify and verify temporal properties of drug disposition changes is proposed. In pharmacokinetics and pharmaceutics, drug kinetics is often modeled as single or multiple compartment models. In this paper, a probabilistic temporal logic, called iLTL, is introduced to specify many interesting properties of drug kinetics. Given a specification, a computerized techni...

Nicotine is of importance as the addictive chemical in tobacco, pharmacotherapy for smoking cessation, a potential medication for several diseases, and a useful probe drug for phenotyping cytochrome P450 2A6 (CYP2A6). We review current knowledge about the metabolism and disposition kinetics of nicotine, some other naturally occurring tobacco alkaloids, and nicotine analogs that are under develo...

.. OBJECTIVE: The study was planned to observe the bioavailability and disposition kinetics of amoxicillin in adult rabbits (irrespective of sex) under healthy and dehydrated conditions. Design: Comparative. Place and duration of study: The study was conducted at the department of pharmacology, University of Veterinary and Animal Sciences, Lahore from April 2013 to October 2013. Methodology: In...