TRPV3 ion channels mediate thermo-transduction, nociception, inflammation and dermatitis in mammals. TRPV1-4 proteins have been shown to have conserved cysteine-residues in the pore-forming regions. These residues participate in channel activation via S-nitrosylation of channel proteins. Camphor is a commonly used ligand for TRPV3 channels. Thus the knowledge about the potential binding/interac...

Many essential oils and monoterpenes are used therapeutically as relaxing drugs and tranquilizers. In this study, ten structurally related monoterpene alcohols, present in many essential oils, were evaluated in mice to investigate their pharmacological potential in the central nervous system. Isopulegol (1), neoisopulegol (2), (+/-)-isopinocampheol (3), (-)-myrtenol (4), (-)-cis-myrtanol (5), (...

Senescence-induced therapy has been improved to increase its cytotoxicity and reduce the resistance of breast cancer cells chemotherapy agents. An example a potential senescence-inducing agent is black cumin oil (BCO) because one major compounds, α-pinene, can induce senescent cells. This study aims explore activity BCO in HER2-overexpressing (MCF7/HER2). The yield obtained from hydro-distillat...

Achillea millefolium belong to the asteraceae family and from genus achillea. In this study essential oils were extracted from all aerial parts via hydro distillation (HD) method by clevenger set . By using of gas chromatography/mass spectrometry ( GC-MS) technique the chemicals component essential oil were identified. About 41 components with were identified which encompassed 97.66 percent of ...

The aim of the present study was to investigate chemical composition and antibacterial activity of essential oil from the leaf of Mentha spicata plant against common food-borne pathogenic bacteria (Staphylococcus aureus, Bacillus subtilis, Bacillus cereus, Listeria monocytogenes, Salmonella typhimurium, and Escherichia coli O157:H7). Chemical composition of the essential oil was identified by g...

achillea millefolium belong to the asteraceae family and from genus achillea. in this study essential oils were extracted from all aerial parts via hydro distillation (hd) method by clevenger set . by using of gas chromatography/mass spectrometry ( gc-ms) technique the chemicals component essential oil were identified. about 41 components with were identified which encompassed 97.66 percent of ...

spearmint (mentha spicata l.) is one of the most important mint family plants that has numerous applications in food, cosmetical, and pharmaceutical industries due to its valuable medicinal properties. in this research, the change in plant fresh and leaf dry weights, essential oil content, yield and composition during year as randomized complete block design with twelve treatments and three rep...

The goal of this study was to verify the suitability of using fatty acids (FAs), terpenoids, and electronic nose response as potential tracers of the seasonal variations in Asiago d’Allevo PDO cheese. Cheese samples produced during the early and late summer grazing and the autumn/winter indoor seasons were compared. Based on their FA composition, the early and late summer cheeses were almost co...