non-hodgkin lymphoma usually presents with generalized lymphadenopathy, but it can also involve any part of the human body. lymphomatous involvement of muscles is a rare presentation and has been reported to occur in only 1.1% in non-hodgkin lymphoma. here we, present a 32 year-old iranian man with primary involvement of spleen, bone, bone marrow and muscle, mimicking soft tissue sarcoma; core ...

diffuse large b-cell lymphoma is the most common type of non-hodgkin lymphoma. micrornas (mirnas) are endogenous small rna, which can regulate gene expression at the post-transcriptional level. mirna profiling has shown a great potential as novel diagnostic and prognostic biomarkers. the present study was performed at the nemazee teaching hospital (shiraz, iran) from 2011 to 2013.the aim of thi...

background and objective: approximately half of patients with diffuse large b-cell lymphoma are cured with current chemotherapy regimens. the purpose of this study was to evaluate bax and bcl2 expression and their relationship with the response to chemotherapy. materials and methods this study was a prospective analysis on 44 patients with diffuse large b-cell lymphoma. their specimens were sta...

background: diffuse large b-cell lymphoma (dlbcl) is an aggressive malignancy of mature b lymphocytes. it is known as a heterogeneous disease with variable therapeutic responses and alternative therapies. morphological and immunophenotypical evaluation of the biopsy specimens can help diagnose dlbcl. methods: in the current study, 44 patients were chosen from shaheed sadoghi hospital (2010–2013...

the authors describe a case of histiocyte-rich b-cell lymphoma (hr-bcl), a variant of diffuse large b-cell lymphoma, in a 51-year-old man. the patient presented with large axillary lymphadenopathy. histopathologic and immunohistochemical examination of lymph node biopsy revealed diffuse effacement of the lymph node architecture by reactive histiocytes and neoplastic cd20 positive b cells. react...

intravascular large b-cell lymphoma (ivlbcl) is a rare and aggressive subtype of systemic extranodal non-hodgkin diffuse large b-cell lymphoma (dlbcl). we report a rare case of ivlbcl who showed diffuse 18f-fluorodeoxyglucose (fdg) uptake in the lung in fdg-positron emission tomography/computed tomography (pet/ct) without respiratory symptoms or chest ct abnormalities. serum biochemical studies...

The authors describe a case of histiocyte-rich B-cell lymphoma (HR-BCL), a variant of diffuse large B-cell lymphoma, in a 51-year-old man. The patient presented with large axillary lymphadenopathy. Histopathologic and immunohistochemical examination of lymph node biopsy revealed diffuse effacement of the lymph node architecture by reactive histiocytes and neoplastic CD20 positive B cells. ...

primary hepatic lymphoma is a rare malignancy usually presenting with symptoms of fever, hepatomegaly, jaundice and weight loss. this picture mimics infectious and inflammatory disorders and thus delays the diagnosis. here, we present a 47-year old man with prolonged fever who underwent several investigations and, in the meantime, developed fulminant hepatic failure before the diagnosis could b...

a 45-year-old female patient with a diagnosis of ulcerative colitis complicated with composite lymphoma in the spleen and para-aortic lymph node presented with a one-month history of malaise, weakness and fatigue. only mesalamine kept ulcerative colitis under control. in physical examination, splenomegaly was revealed and pancytopenia was obtained from laboratory data. computed tomography scan ...

primary non-hodgkin’s lymphoma of the cranial vault is extremely rare. this case report presents a 42-year-old man with a painless subcutaneous scalp mass which extended intracranially associated with recent mild headache. initial computed tomography and magnetic resonance imaging revealed two lesions emanating from the skull. biopsy revealed a diagnosis of diffuse large b cell lymphoma (dlbcl)...