A double-blind comparison of meglumine iodamide and Renografin 60 (52% meglumine diatrizoate and 8% sodium diatrizoate) for bolus excretory urography was performed. Doses of 0.8 cc/kg. to a maximum of 55 cc were administered to fifty patients, twenty-five receiving each drug.There is a suggestion that iodamide may be superior to diatrizoate in pyelocalyceal opacification while being equal to di...

Objective: To investigate the liver-injury of the SD rats in autologus orthotopic liver transplatation using Meglumine Diatrizoate and Omnipaque. Methods: The portal veins of 60 healthy SD rats were perfused to set up orthotopic liver autotransplatation models. Then the external drainages of rats’ bile duct were built up by bile duct cannula. The ALT and AST in blood serum were detected 24h and...

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An ideal coronary vasodilator for studying coronary flow reserve in humans would rapidly produce maximal coronary vasodilation, be short acting to permit repeated measurements, and not alter systemic hemodynamics. The two commonly used vasodilators (dipyridamole and meglumine diatrizoate) do not satisfy these criteria; meglumine diatrizoate does not produce maximal hyperemia and dipyridamole ha...

lohexol is a new, non ionic water-soluble contrast agent undergoing early clinical trials in the United States. Using a doubleblind , parallel format, iohexol was compared with meglumine iothalamate (60 patients) for selective cerebral angiography, and with sodium meglumine diatrizoate (40 patients) for arch aortography. lohexol produced significantly less pain than meglumine iothalamate or sod...

background small bowel obstruction is one of the most common surgical emergencies and main causes of hospital admissions. diatrizoate meglumine gastrografin, a hyperosmolar water-soluble contrast agent, has been used to triage patients with small bowel obstruction for an operative or a non-operative management. it can also have a therapeutic effect by increasing the pressure gradient across obs...

Meglumine diatrizoate ("Renografin-76", a radiographic contrast medium) contains sufficient nickel to cause hypernickelemia in patients after coronary arteriography. Nickel analyses by electrothermal atomic absorption spectrophotometry showed that nine lots of "Renografin-76" (760 g of meglumine diatrizoate per L) contained 144 +/- 44 micrograms Ni per L. Serum Ni concentrations became elevated...

Iohexol is a nonionic water-soluble iodinated contrast medium with chemical and physical properties similar to those of metrizamide. A randomized double-blind study was performed in 40 patients undergoing intravenous digital subtraction angiography for suspected carotid and vertebral disease to compare the radiographic imaging quality and side effects of iohexol with those of Renografin-76 (dia...