?2 microglobulin (?2m) fibril has been recognized as the major factor of dialysis-related amyloidosis. elevated serum levels are thought to be the basis for tissue deposition. in order to evaluate the effect of cellulosis membrane (fb 110) and treatment duration on s?2m levels, we determined serum levels in 23 hemodialyzed patients with end-stage renal failure. s?2m levels were markedly elevate...

background several studies have been carried out to evaluate the effects of dialysis on o2 saturation. while the dialysis procedure may lead to hypoxia under different circumstances, there are few studies available on the effects of membrane type on o2 saturation in these patients. objectives this study was to appraise the effects of high and low flux membrane on pulse oxymetery in dialysis pat...

High-flux dialysis membranes used with bicarbonate dialysis fluid increase the risk of back diffusion of bacterial endotoxin into the blood during hemodialysis. Endotoxin transfer of various synthetic fiber membranes was tested with bacterial culture filtrates using an in vitro system testing both diffusive and convective conditions. Membranes were tested in a simulated dialysis mode with endot...

BACKGROUND There is increased oxidative stress in patients undergoing haemodialysis (HD); however, little is known of how different dialysis membranes contribute to the oxidative stress induced by the dialysis procedure per se. We therefore studied the influence of two different dialysis membranes on oxidative stress during HD. METHODS Eight patients undergoing HD three times per week were en...

The choice of dialyzer may affect the dialysis process more than any other single component of the dialysis system. Over the past five decades, membranes used for the treatment of chronic kidney disease have continuously evolved, and the use of classical non-modified cellulose membranes has declined in favor of cellulose-based membranes in which the basic structure has been modified to improve ...

Dialysis reactions with biocompatible membranes are rare, and complement activation has been suggested to be a culprit. We report here a case of an incident haemodialysis patient with asthma disease who experienced severe adverse reactions late into dialysis session, with different synthetic membranes (FX 80, Fresenius; Polyflux 17L, Gambro; FX 10, Fresenius; BLS 512, Bellco-Sorin). After repla...

This study was designed to evaluate the pharmacokinetics of vancomycin during hemodialysis with cellulose triacetate (CT) high-flux dialyzers and to assess the influence of membrane surface area on intradialytic clearance. In a randomized crossover fashion, the pharmacokinetics of vancomycin were evaluated during dialysis with the CT 110 and CT 190 membranes. Six hemodialysis patients received ...

Background: Improvements in the biocompatibility of dialysis membranes have reduced biological responses elicited by blood–membrane interactions. In this article, recent technological developments in dialysis membranes with regard to biocompatibility and recent progress in the evaluation of the biocompatibility of dialysis membranes are reviewed. Summary: The focus of investigation into dialysi...

Background: Improvements in the biocompatibility of dialysis membranes have reduced biological responses elicited by blood–membrane interactions. In this article, recent technological developments in dialysis membranes with regard to biocompatibility and recent progress in the evaluation of the biocompatibility of dialysis membranes are reviewed. Summary: The focus of investigation into dialysi...