نتایج جستجو برای: diabetic heart
تعداد نتایج: 493351 فیلتر نتایج به سال:
grape seed proanthocyanidin (gsp) bears a very powerful antioxidant effects. studies demonstrated that proanthocyanidins protect against free radicals mediated cardiovascular and renal disorders. the present study was designed to assess the effect of gsp on the heart of diabetic rats. forty rats were divided into four groups of 10 animals each: group i: control, group ii: control group were giv...
results among the patients enrolled, 61 had microalbuminuria (uacr, 30-299) and 133 normoalbuminuria (uacr, < 30). patients with normoalbuminuria showed significantly higher levels of gal-3 than those without (19.9 ± 8.8 vs. 14.6 ± 5.5 ng/ml). the stepwise regression analysis indicated that gal-3 was the first determinant of microalbuminuria (odds ratio [or]: 1.08; 95% confidence interval [ci]:...
abstract objective: the previous studies indicated that the tlrs especially toll-like receptor 4) tlr4 (are involved in the process of diabetes. the aim of the present research was to investigate the time course expression pattern of tlr4-a main component of innate immune system- in mrna levels in the heart tissue of diabetic male wistar rats. materials and methods: in this research, adult wist...
background: to assess the effect of supplementation with vitamins a, e and c and ω-3 fatty acids on lipid peroxidation in strepto zotocin (stz) induced diabetic rats. methods: sixty four male wistar rats weighting 250g were divided into four groups as normal control, diabetic control, dia betic with vitamin a, e as well as c supplementation and diabetic with ω-3 fatty acids supplementation. aft...
background: overexpression of lectin-like low density lipoprotein (lox-1) receptor plays an important role in hyperglycemia-induced vascular complications such as atherosclerosis. based on the beneficial effects of exercise on preventing cardiovascular complications of diabetes, we aimed to examine the protective effects of aerobic exercise on expression of lox-1 receptor and production of free...
Background: Diabetic cardiomyopathy is the first cause of death in diabetic patients and angiogenesis is the most important mechanism for the recovery of heart blood flow in physiologic and pathologic conditions. The purpose of this study was to compare the effect of eight weeks of moderate continuous and sever interval training on heart angiogenesis in Wistar male diabetic rats. Methods: 32 W...
Background and Aim: One of the most common metabolic diseases is diabetes with hyperglycemic properties and endogenous insulin dysfunction. This study aimed to evaluate the effect of 10 weeks HIIT on HIF-1α gene expression in heart tissue of rats with type 2 diabetes. Methods: In this experimental study, 36 Wister rats with a mean weight of 200±58g were randomly assigned to control, diabetic,...
Introduction: Oxidative stress can promote the development of complications of diabetes. Moderate exercise improves cardiac antioxidant status in diabetic animals. The current study aimed to investigate the effect of 8 week endurance exercise training on some heart antioxidant enzyme activities and lipid peroxidation of heart tissue in streptozotocin-induced diabetic rats. Methods: To this e...
cardiovascular disease is the common cause of mortality in diabetic subjects. recently, it is indicated that peroxisome proliferator-activated receptors (ppars) agonists have beneficial effect on cardiovascular system especially on angiogenesis. ppars have three isotypes: pparα, pparβ/δ and pparγ. in this study, we evaluated the effect of bezafibrate as pan ppar agonist on myocardial capillary ...
Background: Diabetes mellitus in pregnancy can cause heart histological changes. This study was done to evaluate the effect of barly grain (Hordeum Vulgar L.) consumption during pregnancy in diabetic rats on heart histological altrations of offsprings. Methods: In this experimental study ,60 adult female albino rats, randomly allocated into four groups including: healthy group with regul...
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