homeobox (hox) genes are contributed in the genetic control of development of the body plan, pattern formation, and cell fate determination and the other several key developmental processes. hox genes are also known as selector genes because expression within a given section of the embryo will cause its cells to choose a particular developmental path. hox genes encode transcription factors that...

The evolution of body form is believed to involve changes in expression of developmental genes, largely through changes in cis-regulatory elements. Recent studies suggest that changes in the sequences of key developmental regulators, such as the Hox proteins, may also play an important role.

background: embryo cryopreservation is the process that water is removed from the cell by cryoprotectant materials, and embryos are stored at temperature below zero. this process may affect the viability and developmental potential of embryos. objective: in this study, the effect of the vitrification cryotop method on the expression level of oct4 and mest developmental genes in mouse blastocyst...

Multicellular organisms are composed of groups of different cell types. The importance in the evolution of cellular diversity of regulatory changes in genes that control cell specification has been revealed by a recent study of developmental genes in Arabidopsis.

Background Little is understood about the regulation of gene expression during early goat embryo development. This study investigated the expression profile of 19 genes, known to be critical for early embryo development in mouse and human, at five different stages of goat in vitro embryo development (oocyte, 8-16 cell, morula, day-7 blastocyst, and day 14 blastocyst). MaterialsAndMethods Stage-...

The shaping of the early embryo requires pattern formation as well as geometric and topological morphogenesis of the developing tissues. The morphogenetic movements that lead to geometric shape changes are controlled by patterned gene expression. How particular movements are related to patterning genes, and which underlying molecular and cellular mechanisms lead to coordinated macroscopic movem...

Regulatory gene circuits enable stem and progenitor cells to detect and process developmental signals and make irreversible fate commitment decisions. To gain insight into the gene circuits underlying T cell fate decision making in progenitor cells, we generated an updated T-lymphocyte developmental gene regulatory network from genes and connections found in the literature. This reconstruction ...