BACKGROUND The plasma effect-site equilibrium rate constant (k(e0)) of propofol has been reported in various pharmacodynamic studies; however, it is not desirable to apply k(e0) for the link with pharmacokinetic models that were separately investigated. Thus, we titrated k(e0) for the pharmacokinetic model, which is known as the multiple covariates adjusted model of propofol. METHODS Ninety f...

We present a demonstration of the unambiguous determination of two-photon absorption 2PA and three-photon absorption 3PA in semiconductor quantum dots in the vicinity of E0 /2, where E0 denotes the peak position of the lowest exciton energy. In the spectral region where photon energies E0 /2, the 2PA cross section is determined by open-aperture Z scans with femtosecond laser pulses at relativel...

Mice deficient in both macrophage-colony-stimulating factor (M-CSF, op) and apolipoprotein E (apoE) have elevated cholesterol levels but are protected from atherosclerosis. To assess the contribution of macrophage (Mphi) phenotypic heterogeneity and scavenger receptor (SR-A) expression to this seeming paradox, we characterized the Mphi phenotype by immunohistochemistry in these animals. Lesion ...

We have developed an ultrasonic technique for determining the dynamic Young's modulus of elasticity (E) of the canine aorta in vivo. Young's modulus was measured in the descending thoracic aorta (DTA) and the abdominal aorta (AA) of 12 dogs over a range of mean blood pressures from 40-200 mmHg. The vessels were excised and dynamic moduli were determined in vitro postmortem from pressure-volume ...

Numerical experiments carried out systematically using the Lee Model code unveil insightful and practical wide-ranging scaling laws for plasma focus machines for nuclear fusion energy as well as other applications. An essential feature of the numerical experiments is the fitting of a measured current waveform to the computed waveform to calibrate the model for the particular machine, thus provi...

This paper is devoted to analytic vector fields near an equilibrium for which the linearized system is split in two invariant subspaces E0 (dim m0), E1 (dim m1). Under light diophantine conditions on the linear part, we prove that there is a polynomial change of coordinate in E1 allowing to eliminate, in the E1 component of the vector field, all terms depending only on the coordinate u0 ∈ E0, u...

The redox potentials of poplar plastocyanins a and b (PCa, PCb) were determined by spectrophotometric titrations of their reduced forms with [Fe(CN)6]3-. It was found that the two isoforms have the following millimolar extinction coefficients epsilon597 equilibrium constants Keq of one-electron exchange with [Fe(CN)6]4-/[Fe(CN)6]3-, and standard electron potentials E0: PCa: epsilon597 = (4.72 +...

We report a direct square-wave voltammetric study of the iron-sulfur enzyme, aconitase, at the pyrolytic graphite edge electrode. New and established redox driven reactions were observed and the equilibrium reduction potential for each couple was determined: E0'[3Fe-4S]1+/0 = -268 mV, E0'[4Fe-4S]2+/1+ = -450 mV, E0'[4Fe-4S]3+/2+ = +100 mV, E0'Linear Form = -281 mV, and putatively, E0'[3Fe-4S]0/...

  Background :There is substantial lack of knowledge about the role of socioeconomic status (SES) indicators on life expectancy (LE) within-cities, especially within mega-cities. We aimed to investigate the disparities of LE within city districts of Tehran, Iran, and specify how SES inequalities play role on LE.   Methods : The death and population data for 2010 by different age, gender, and re...