نتایج جستجو برای: derived growth factor
تعداد نتایج: 1850426 فیلتر نتایج به سال:
چکیده با وجود اینکه توجه قابل ملاحظه ای بر اهمیت جنبه های تکنیکی جراحی ترمیم عصب می شود، به نظر می رسد که فاکتورهای رشد از جمله فاکتور رشد عصبی (nerve growth factor (ngf)) فاکتور نروتروفیک مشتق از مغز ((brain-derived neurotrophic factor (bdnf) و نوروتروفین 3 (neurotrophin3 (nt3)) میزان تولید سلول های عصبی را تحت تأثیر قرار می دهند. هدف از مطالعه ی حاضر بررسی این موضوع است که آیا عصاره ی خام مغ...
مقدمه: از کارامدترین روش های ترمیم آسیب های بافتی، سلول درمانی است. امروزه از سلول های msc (mesenchymal stem cell) به دلیل قدرت بالای تمایز به انواع سلول ها و ترشح فاکتورهای رشد متعددی همچون pdgf (platelet derived growth factor) و sdf-1α (stromal cell-derived factors-1alpha) برای این منظور استفاده می شود. هورمون های جنسی با اثر بر میزان ترشح این فاکتورها، تکثیر و مهاجرت سلول ها و فرایند های ترم...
background: the present study investigated the functional maturity of oligodendrocyte derived from rat bone marrow stromal cells (bmsc). methods: the bmsc were isolated from female sprague-dawley rats and evaluated for different markers, such as fibronectin, cd106, cd90, oct-4 and cd45. transdifferentiation of olc from bmsc was obtained by exposing the bmsc to dmso and 1 µm all-trans-retinoic a...
conclusions this study shows that bdnf and ngf expression decreases in diabetic neuropathy. however, this decrease can be reversed through endurance training. these results also indicate that endurance training may have a potential role in compensating for neurotrophin deficiency following diabetic neuropathy. objectives this experimental study was designed and carried out at the tarbiat modare...
conclusions tissue engineering may open a new window in cleft palate reconstruction. stem cells and growth factors play key roles in this field. results we reported a summary of the key-points concerning cleft palate development, the genes involving this defect, current therapeutic strategies, recently novel aspects, and future advances in treatments for easy and fast understanding of the conce...
background and aims. plasma rich in growth factors (prgf) is a concentrated suspension of growth factors, which is used to promote periodontal tissue regeneration. the aim of this randomized, controlled, clinical trial was to evaluate of the treatment of grade ii mandibular molar furcation involvement using autogenous bone graft with and without prgf. materials and methods. in this double-blind...
abstract background autologus platelet gel is easy to prepare and is relatively low cost. the aim of this study was to prepare and evaluate in vitro efficacy of autologus platelet gel. materials and methods in this experimental study, platelet concentrate and platelet poor plasma were prepared with aphaeresis method. thrombin was prepared by mixing the plasma with calcium. thrombin activity lev...
background: the anticancer agent imatinib (im) is a small molecular analog ofatp that inhibits tyrosine kinase activity of platelet derived growth factors (pdgfs)and stem cell factor (scf) receptor in cancer cells. however these factors have a keyrole in regulating growth and development of normal sertoli, leydig and germcells.objective: the aim of this study was to determine cell viability, pd...
background: osteoarthritis is one of the most common diseases in middle‑aged populations in the world and could become the fourth principal cause of disability by the year 2020. one of the critical properties for cartilage tissue engineering (te) is the ability of scaffolds to closely mimic the extracellular matrix and bond to the host tissue. therefore, te has been presented as a technique to ...
Background and Objectives: Different diets have important roles in human health and aging. In the current study, we aimed to characterize the Klotho, an anti-aging protein, gene expression and protein level in the serum and assess the protein levels of Transforming growth factor-β and Platelet-derived growth factor in old rats which treated with different diets (high-fat, high-protein, low calo...
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