نتایج جستجو برای: dentinogenesis

تعداد نتایج: 320  

Journal: :Journal of endodontics 2010
Stephane Simon Anthony J Smith Ariane Berdal Philip J Lumley Paul R Cooper

INTRODUCTION We have previously shown that the p38 gene is highly expressed in odontoblasts during active primary dentinogenesis, but is drastically down-regulated as cells become quiescent in secondary dentinogenesis. Based on these observations, we hypothesized that p38 expression might be upregulated, and the protein activated by phosphorylation, when odontoblasts are stimulated such as duri...

2014
Markku Larmas George K. B. Sándor

OBJECTIVES Search in PubMed with keywords "enzymes, dentinogenesis, and dental caries" revealed only 4 items, but when combined with "enzymes, osteogenesis, and osteoporosis" as high as 404 items resulted. Dental caries was associated with an order of magnitude fewer studies than the chronic bone disease, osteoporosis. This observation motivated this review. MATERIAL AND METHODS A comprehensi...

Journal: :medizinische genetik 2007

2017
Francisco José Reis Gama Isabella Sousa Corrêa Claudia Scigliano Valerio Emanuelle de Fátima Ferreira Flávio Ricardo Manzi

Dentinogenesis imperfecta is a dominant autosomal hereditary disorder of dentin formation that affects the deciduous and permanent teeth. Its etiology is characterized by inadequate cell differentiation during odontogenesis. The clinical characteristics of dentinogenesis imperfecta are discolored teeth with a translucency that varies from gray to brown or amber. Radiographically, the teeth exhi...

Journal: :Caries research 2004
D Tziafas

The ultimate goal of a regenerative pulp treatment strategy is to reconstitute normal tissue continuum at the pulp-dentin border, regulating tissue-specific processes of tertiary dentinogenesis. Experimental investigations in mature teeth have shown that a network of extracellular matrix molecules and growth factors signal tertiary dentinogenesis. Application of dentin matrix components or grow...

Journal: :International endodontic journal 2012
M Frozoni A Balic K Sagomonyants A A Zaia S R P Line M Mina

AIM To examine the feasibility of using the pOBCol3.6GFPtpz [3.6-green fluorescent protein (GFP)] transgenic mice as an in vivo model for studying the biological sequence of events during pulp healing and reparative dentinogenesis. METHODOLOGY Pulp exposures were created in the first maxillary molar of 12-16-week-old 3.6-GFP transgenic mice with CD1 and C57/Bl6 genetic background. Direct pulp...

Journal: :The journal of contemporary dental practice 2013
Naresh Lingaraju P J Nagarathna R Vijayalakshmi P Sheshadri

Osteogenesis imperfecta is a collagen related disorder characterized by increased bone fragility and low bone mass. The important oral finding in osteogenesis imperfect is the presence of dentinogenesis imperfecta. This article presents a case of osteogenesis imperfecta (type IV B) with dentinogenesis imperfecta where a 7-year-old girl had opalacent primary teeth associated with severe bone def...

Journal: :Clinical and Laboratorial Research in Dentistry 2020

Journal: :STOMATOGNATIC - Jurnal Kedokteran Gigi 2019

2003
ESA PEKKALA Juha Tuukkanen Markku Larmas

The effects of dietary sucrose feeding, intragastric sucrose feeding and dietary calcium-deficiency on primary dentinogenesis of the pulp-dentin organ and caries progression were examined in an experimental rat model. The possible role of calcium balance and reduced mineralization of dentin organic matrix as a cause of reduced dentin formation in young, fast growing, rats were also studied. Dur...

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