evaluation of enlarged follicles with unerupted teeth is always important because some changes may occur. one of the extremely rare conditions seen in dental follicles is multiple calcifying hyperplastic dental follicle. we report a case of multiple calcifying hyperplastic dental follicle. radiographs showed that mandibular third molars had a pericoronal radiolucent zone delineated by a well-de...

case presentation a 13-year-old boy, in the case presented in this article, had 15 unerupted teeth, each associated with hyperplastic pericoronal tissue. conclusions the purpose of this article is to report an example of this entity and describe the histopathologic characteristics that helps diagnose and treat such condition in the most appropriate manner. introduction pathologic changes may oc...

Adult stem cells are multipotent and can be induced experimentally to differentiate into various cell lineages. Such cells are therefore a key part of achieving the promise of tissue regeneration. The most studied stem cells are those of the hematopoietic and mesenchymal lineages. Recently, mesenchymal stem cells were demonstrated in dental tissues, including dental pulp, periodontal ligament, ...

Purpose: To examine osteoblastic genes expression of freshly isolated human dental follicle cells during osteogenic differentiation in vitro using cDNA microarrays. Materials and Methods: The dental follicle cells isolated from dental follicle were cultured in DMEM media with 10 mol/L Dex for 4 weeks, the control without Dex. Total RNA was extracted from the cultured follicle cells with Trizol....

STATEMENT OF THE PROBLEM The presence of impacted third molars in the jaws is a common finding in the routine dental examination of patients. Concerning the odontogenic components of the dental follicle, it can be the origin of different types of odontogenic cysts and tumors. PURPOSE The aim of this study was to find feasible radiographic criteria to help differentiate between normal and path...

Dental follicle stem cells are a group of cells possessing osteogenic, adipogenetic and neurogenic differentiations, but the specific mechanism underlying the multilineage differentiation remains still unclear. Great attention has been paid to bone morphogenetic protein-9 (BMP-9) due to its potent osteogenic activity. In the present study, rat dental follicle stem cells were isolated and purifi...

An impacted left mandibular second molar (tooth 37) was extracted, but most of its dental follicle remained in the socket. The crown and dental papilla of an unerupted, left mandibular third molar (tooth 38) were then placed into the socket of tooth 37. Successful interaction between the dental follicle of tooth 37 and the crown and dental papilla of tooth 38 led to the formation of a new tooth...

Evaluation of enlarged follicles with unerupted teeth is always important because some changes may occur. One of the ex-tremely rare conditions seen in dental follicles is multiple calcifying hyperplastic dental follicle. We report a case of multi-ple calcifying hyperplastic dental follicle. Radiographs showed that mandibular third molars had a pericoronal radiolucent zone delineated by a well-...

The odontogenic fibroma is a rare, benign tumor of mesodermal origin, and one of the most ill-defined and least understood of all odontogenic neoplasms. 1 It presently is thought to originate from either dental follicle, periodontal ligament, or dental papilla. 2 Bhaskar reported the lesion as being the most common odontogenic tumor comprising approximately 23°70 of all odontogenic lesions. 3 T...

The human dental follicle partially differentiates into the periodontal ligament (PDL), but their biological functions are different. The gene-expression profiles of the dental follicle and PDL were compared using the cDNA microarray technique. Microarray analysis identified 490 genes with a twofold or greater difference in expression, 365 and 125 of which were more abundant in the dental folli...