objective(s): the aim of present research was to develop matrix-mini-tablets of lornoxicam filled in capsule for targeting early morning peak symptoms of rheumatoid arthritis. materials and methods:matrix-mini-tablets of lornoxicam were prepared by direct compression method using microsomal enzyme dependent and ph-sensitive polymers which were further filled into an empty hpmc capsule. to asses...

TRLs have the benefit of providing a common understanding of the status of a technology in its development pathway, a means of assessing and managing risk, and decision making concerning funding and implementation of technology. As with any management tool, there are certain limitations and disadvantages to its use. These include the creation of extra reporting, paperwork, reviews, lengthy adop...

Dent’s disease (MIM #300009) is a rare X-linked disorder characterized by various degrees of proximal tubular (PT) dysfunction, nephrocalcinosis and nephrolithiasis. The exact prevalence is unknown. The disease was first reported by Dent and Friedman, who described two males with vitamin D resistant rickets, hypercalciuria and low molecular weight proteinuria (LMWP) (Dent & Friedman, 1964). Bas...

Maria Doukantzi, Dr Med Dent/Philippe Mojon, Dent/Ana Todorovic, Dent/Najla Chebib, Dent/Bjarni Elvar Pjetursson, Prof Dent, PhD/Sabrina Maniewicz, Dent/Irena Sailer, Dent: Purpose: To investigate the differences in accuracy (ie, trueness and precision) of five different optical impression systems. Materials Methods: The following systems was tested: (1) CEREC Bluecam (BL); (2) Omnicam (OM); (3...