Back Cover: The blood plasma protein fibrinogen can assemble into fibers in vitro based on different mechanisms. Self-assembly is either induced by denaturing buffers, non-denaturing buffers or substrate interactions. Understanding how these factors influence fibrillogenesis important for developing fibrinogen-based biomaterials with fibrous architecture future tissue engineering applications. ...

In this paper, we describe denaturing and non-denaturing ion-pair reversed-phase liquid chromatography (RPLC) methods for analyzing small interfering ribonucleic acid (siRNA). Drug formulations consisting of one or two siRNA duplexes were analyzed in conditions at a low column temperature to separate intact from single-stranded oligonucleotide contaminants quantify them. method, used an elevate...

Introduction Nature is a ubiquitous and powerful word that has been significant for understanding and endorsing forms of being and relationship throughout Western history. However, nature’s meanings—especially the social-relational significations that it carries—have varied over time, according to a range of contexts and “controlling images.”1 Nature is decidedly historical. Its myriad interpre...

DESCRIPTION A 39-year-old man presented with intense pain and cellulitis in his right hand following a lionfish sting. Because of the rarity of lionfish stings in the United Kingdom, signs, symptoms, and optimal management for this injury are not widely known. Thus we attempt to highlight them through this case.

Denaturing High-Performance Liquid Chromatography (DHPLC) is a recently developed technique forthe detection of single nucleotide polymorphisms (SNPs) and mutations. It involves the comparisonbetween two or more DNAs as a mixture of denatured and reannealed PCR products. The methodologyis based on the principle of reversed phase liquid chromatography and uses a unique DNA sepa...

the objective of this study was to explore the microbial community diversities and the relationships between microbial community compositions and hydrochemical factors in nitrate contaminated groundwater of hun river alluvial plain. the method of polymerase chain reaction (pcr)-denaturing, gradient gel electrophoresis (dgge) gene fingerprints combined with canonical correspondence analysis（cca）...