Canine demodicosis is a common parasitic skin disease in dogs. It can be classified into 2 types based on distribution of lesion; localized and generalized demodicosis. Localized demodicois was reported to be usually spontaneous remission, therefore, no treatment is needed. Generalized demodicosis, on the other hand, cannot heal spontaneously so miticidal therapy should be prescribed. However, ...

Using RT-PCR and semi-quantitative PCR, mRNA expression for canine interferon (IFN)-gamma, interleukin (IL)-2, IL-4, IL-5, IL-10, tumor necrosis factor (TNF)-alpha and transforming growth factor (TGF)-beta in peripheral blood mononuclear cells (PBMCs) was examined in dogs with or without demodicosis. mRNA expression for IFN-gamma as well as TNF-alpha in dogs with demodicosis (localized (LD) and...

Background: Canine demodicosis is an inflammatory parasitic skin disease associated with the presence of excessive numbers of Demodex mites. The pathogenesis involving demodicosis is not completely recognized. It is suggested that demodicosis occurs because of the inability of the host to regulate mite intensity, rather than from an elevation of the mite virulence. The acute phase response is a...

PURPOSE To investigate the correlation between demodicosis and chalazia in patients with the latter. DESIGN Prospective, observational, comparative study. METHODS Forty-four adult and 47 pediatric patients with chalazia and 34 adult and 30 pediatric age- and sex-matched patients without chalazia treated at an institutional referral eye center were included. All 155 patients underwent lash s...

Demodex spp may cause blepharitis and palpebra skin lesions. Since eyelash demodicosis seems to be quite spreadable in the community, every patient with chronic non-diagnosed blepharitis should be examined for Demodex spp. Tea tree oil treatment may be an efficient and safe therapeutical choice against ocular demodicosis.

BACKGROUND Demodicosis is a parasitic skin disease caused by Demodex mites, and the determination of mite density per square centimeter is important to diagnose demodicosis. Standardized skin surface biopsy (SSSB) and direct microscopic examination (DME) are commonly used to determine Demodex mites density (Dd). However, no study has previously compared these two methods with respect to clinica...

© 2012 The Authors. doi: 10.2340/00015555-1200 Journal Compilation © 2012 Acta Dermato-Venereologica. ISSN 0001-5555 Demodex mites may play a pathogenic role when present in excessive numbers or when penetrating into the dermis. There are two types of mites. Demodex folliculorum is usually found in the follicular infundibulum, and D. brevis in sebaceous ducts and meibomian glands (1, 2). Pityri...

Canine demodicosis is a common noncontagious parasitic dermatosis caused by different spp of Demodex mites including Demodex canis, Demodex injai and D. cornei. Generalized demodicosis can be one of the most frustrating skin diseases, one will ever treat. Conventional and newer miticidal therapies are available to veterinarian to treat this frustrating skin disease. All recognized Demodex mites...

During the period 1993-2003, generalized demodicosis was diagnosed in 517 dogs. Two hundred and sixty-five (51.2%) dogs were cured with amitraz 0.025% solution, 199 (38.5%) were cured after amitraz 0.05% solution was introduced, and in 53 dogs (10.3%) mites were amitraz resistant. Among amitraz-resistent dogs, 48 were introduced to 600 μg kg-1 oral ivermectin protocol, and 45 (89.6%) of this nu...