BACKGROUND Our aim was to explore the de-addiction properties of Delphinium denudatum Wall. in morphine dependent rats. METHODS Charles Foster male albino rats were made morphine dependent by injecting morphine sulphate in increasing doses twice a day for 7 days. The spontaneous withdrawal signs observed 12 h after the last dose were quantified by the 'counted' and 'checked' signs. The drug (...

Introduction: In our modern era, life style of human being changes and updates every day that may affect their health status. There is an incredible expectation that natural origin drugs lack undesirable effects not like synthetic drugs, though have the same potency and efficacy. No scientific data is available about the antianxiety properties of Delphinium denudatum root and Amaranthus spinosu...

Delphinium denudatum known as Jadwar, is critically enlarged Himalayan herbs, which was once commonest species. It is distinguished by its relatively small blue or violet color and it is one of the important drugs used as indigenous medicine in India, especially in Unani medicine system. A number of studies have been done on its phytochemical and pharmacological properties. Bioactive constituen...

Isolation of a number of bioactive compounds from medicinal plants such as acetylcholinesterase inhibiting steroidal alkaloids, homomoenjodaramine and moenjodaramine from Buxus hyrcana, anti-epileptic terpenoids delphadienones I and II from Delphinium denudatum, and potent leishmanicidal compound ajoene from Allium sativum have been achieved through bioactivity-guided isolation.

Chronic treatment with Delphinium denudatum (Dd) (Jadwar) (family: Ranunculaceae, 200-1600 mg/kg) suppressed morphine withdrawal jumps in a dose-dependent manner, a sign of the development of dependence to opiate as assessed by naloxone (2 mg/kg) precipitation withdrawal on day 10 of testing in mice. Repeated administration of Dd (200-1600 mg/kg) for 9 days attenuated the development of toleran...

The value-added channa was optimized for its processing with the incorporation of 3% Lycium barbarum and 0.25% Delphinium denudatum. value added standardized subjected to an in vitro antioxidant profile analysis total phenols, flavonoids content, DPPH, ABTS FRAP assays product storage profile. prepared denudatum having a shelf life more than three weeks stored at refrigeration temperature. Thus...