HYPOTHESIS Albuterol delivery through a tracheostomy tube is affected by device (nebulizer vs metered-dose inhaler), interface (mask vs T-piece), bias flow, and humidification. METHODS A lift bar was placed between the chambers of a dual-chambered lung model such that a ventilator triggered simulated spontaneous breathing at a rate of 20 breaths/min, tidal volume of 0.4 L, and inspiratory-exp...

Patents: To deliver drugs to patients on mechanical ventilation, the drug particles have to successfully navigate through an endotracheal tube and the ventilator tubing. Liquid formulations (e.g. nebulized) normally used with these patients are inefficient. Large amounts of drugs are deposited in the endotracheal tube and within the ventilator circuit. Dry powders offer an alternative formulati...

Dose delivery of hydrofluoroalkane-beclomethasone and chlorofluorocarbon-beclomethasone was compared during in vitro neonatal simulations: mechanical ventilation with 40% and 100% relative humidity + Neonatal Chamber-Ventilator System/endotracheal tube; manual ventilation + Neonatal Chamber/endotracheal tube; "spontaneous breathing" + Neonatal Chamber/face mask without/with manual assistance. T...

To the Editor: Bain circuits which we presently use are designed with a coloured delivery tube so that kinks or obstructions to the tube will be easily Seen. We received a new Bain circuit which appeared intact, but when it was placed on the anaesthetic machine, it provided no gas flow at the patient end. On examining the circuit, the delivery tube was obstructed and kinked at the proximal end....