the result of the 6 years study of patients with hydatiform mole (hm) and its malignant degeneration in isfahan are presented. the over all frequency is estimated to be one hm in 440 child births. this frequency has remained relatively unchanged through out the study. increased consumption of meet did not seem to lower the frequency of hydatiform mole in our study. the over all frequency of mal...

introduction wilson’s disease is an autosomal recessive disorder, characterized by a disturbance in copper metabolism that leads to copper overload in different tissues of the body. because of various manifestations of wilson’s disease, physicians should have high index suspicion when patients manifest any type of liver disease, neurologic and psychiatric signs and symptoms. discussion wilson’s...

conclusions significant improvement was noted at womac scale (pain level; 5 points, stiffness level; 2 points, physical function loss; 15 points, and total womac 22 points). osteoarthritis level of the patient was improved to grade i at radiological evaluation after a year. our case is the report that presents radiological evidence in addition to clinical findings of improvement of osteoarthrit...

age related macular degeneration (amd) is the most common cause of visual impairment in the population above 64 years of age in developed countries. most cases of severe vision loss due to amd are caused by exudative changes in the macula. extensive research on amd has led to advances in its prophylaxis and treatment in recent years. photodynamic therapy (pdt) was developed in late 1990's ...

purpose: to investigate the effect of ccl2c-2512t polymorphism on age-related macular degeneration (amd). methods: this study enrolled 48 patients originating from northeast of iran who suffered from dry type amd. the association of c-2518t in the promoter region of ccl2 gene was investigated using polymerase chain reaction (pcr) and restriction fragment length polymorphism (rflp). control grou...

introduction coexistence of wilson’s disease and autoimmune hepatitis has been rarely reported in english literature. in this group of patients, there exist features of both diseases and laboratory and histopathological studies may be misleading. medical treatment for any of these entities, per se, may result in poor response. therefore, by considering the acute hepatitis resembling wilson’s di...

results using these two sets, we identified h1069q mutation in four patients, c.2335t > g mutation in three, c.3061-1g > a splice site mutation in five, c.3305t > c mutation in one, and c.3809a > g mutation in two patients. conclusions the multiplex arms assay used in this study can be an efficient, reliable, and cost effective method as a primary screen for patients with wilson disease. patien...

purpose : to assess the results of intracorneal ring (icr) segments for treatment of patients with pellucid marginal degeneration (pmd) methods : in this prospective interventional case series study, eight eyes of 5 patients with pmd who were contact lens intolerant received one or two intacs (intacs, addition technology) segments. preoperative and postoperative evaluations included slit-lamp e...

background & aim: low back pain is broadly documented as one of the most widespread pathologies in the advanced domain. although the reasons of low back pain are uncountable, it has been meaningfully related to intervertebral disc degeneration. present therapies for intervertebral disc (ivd) degeneration such as physical therapy and spinal fusion reduce symptoms' severity, but do not treat the ...

background: previous researches about the effects of epididymal obstruction on the testes are contradictory, and the mechanism harmful effect of male duct system obstruction on seminiferous tubules still remains unclear. objective: the aim of this study was to investigate the effects of epididymal obstruction in prepubertal rats on the testis. materials and methods: 15 days of age, the young ra...